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  2. Ingredients Used in Pesticide Products

Current and Previously Registered Section 3 Plant-Incorporated Protectant (PIP) Registrations

Revised 7/11/2025

PIP Active Ingredients Registered 1995 – 2025
Active
Ingredient
CommodityYear
Registered
StatusLink To BRAD or other Regulatory Documents1
Cry1Da2 in DAS 1131 (PC Code 006531)Corn2025ActiveRegistration Decision for the New Active Ingredient: Bacillus thuringiensis Cry1Da2 protein and the genetic material (PHP88492) necessary for its production in DAS1131 Maize (OECD Unique Identifier: DAS-Ø1131-3) 
Cry1B.34 in DP910521 (PC Code 006820)Corn2025ActiveRegistration Decision for New Active Ingredient: Bacillus thuringiensis Cry1B.34 Protein and the Genetic Material Necessary (PHP79620) for its Production in DP910521 Maize
Brevibacillus laterosporus Mpp75Aa1.1 in MON 95275 (PC Code 006542)Corn2025ActiveRegistration Decision for the New Active Ingredients: Brevibacillus laterosporus Mpp75Aa1.1, Bacillus thuringiensis Vpb4Da2, and DvSnf7.1 Double Stranded RNA and the Genetic Material Necessary for their Production in MON 95275 Corn (Vector PVZMIR525664)
Bacillus thuringiensis Vpb4Da2 in MON 95275 (PC Code 006541)Corn2025ActiveRegistration Decision for the New Active Ingredients: Brevibacillus laterosporus Mpp75Aa1.1, Bacillus thuringiensis Vpb4Da2, and DvSnf7.1 Double Stranded RNA and the Genetic Material Necessary for their Production in MON 95275 Corn (Vector PVZMIR525664)
DvSnf7.1 Double Stranded RNA in MON 95275 Corn (PC Code 006543)Corn2025ActiveRegistration Decision for the New Active Ingredients: Brevibacillus laterosporus Mpp75Aa1.1, Bacillus thuringiensis Vpb4Da2, and DvSnf7.1 Double Stranded RNA and the Genetic Material Necessary for their Production in MON 95275 Corn (Vector PVZMIR525664)
Cry1B.868 in Event MON 95379 (PC Code 006567)Corn2024ActiveRegistration Decision for the New Active Ingredients Bacillus thuringiensis Cry1B.868 protein and the genetic material (Vector PV-ZMIR522223) necessary for its production in MON 95379 Maize
Cry1Da_7 in Event MON 95379 
(PC Code 006576)
Corn2024ActiveRegistration Decision for the New Active Ingredients Bacillus thuringiensis Cry1Da_7 protein and the genetic material (Vector PV-ZMIR522223) necessary for its production in MON 95379 Maize
IPD072Aa in Event DP23211
(PC Code 006569)
Corn2024ActiveRegistration Decision for the New Active Ingredients: IPD072Aa and DvSSJ1 in DP23211 Maize
DvSSJ1 in Event DP23211
(PC Code 006968)
Corn2024ActiveRegistration Decision for the New Active Ingredients: IPD072Aa and DvSSJ1 in DP23211 Maize
IPD079Ea in Event DP915635
(PC Code 017310)
Corn2024ActiveRegistration Decision for the New Active Ingredient: Ophioglossum pendulum IPD079Ea Protein and the Genetic Material Necessary (PHP83175) for its Production in DP915635 Maize
Cry14Ab-1 and the Genetic Material Necessary for its production (vector pSZ8832)
(PC Code: 006609)
Soybean2020ActiveRegistration Decision for the New Active Ingredient Cry14Ab-1 and the Genetic Material Necessary for its Production (vector pSZ8832) in GMB151 Plant-Parasitic Nematode-Protected Soybean (OECD Unique Identifier: BCS-GM151-6)
Cry51Aa2.834_16 in MON 88702
(PC Code: 006999)
Cotton2018ActiveRegistration Decision for the New Active Ingredient Bacillus thuringiensis Cry51Aa2.834_16 and the Genetic Material (vector PV-GHIR508523) Necessary for its Production in MON 88702 Cotton (OECD Unique Identifier: MON-88702-4
VNT1 in potato
(PC code: 006355)
Potato2017ActiveFinal Registration Decision for the New Active Ingredient and Food Use of VNT1 Protein and the Genetic Material Necessary for its Production in Potatoes
Cry1Ab in event 176
(PC code: 006458)
Corn1995Canceled
(2003)
Biopesticides Registration Action Document - Bacillus thuringiensis Plant-Incorporated Protectants
Cry1Ab in event MON 810 (PDF)
(PC code: 006526)
Corn1996ActiveCry1Ab and Cry1F Bacillus thuringiensis (Bt) (PDF)(253 pp, 1.3 MB, About PDF)
Cry1Ab in event MON 801
(PC code: 006408)
Corn1996Canceled
(1998)
Biopesticides Registration Action Document - Bacillus thuringiensis Plant-Incorporated Protectants
Cry1Ab in event Bt11 (PDF)
(PC code: 006461)
Corn1996ActiveBacillus thuringiensis (Bt) (PDF)(253 pp, 1.3 MB, About PDF)
Cry1Ac in event DBT 418
(PC code: 006463)
Corn1997Canceled
(2000)
Bacillus thuringiensis kurstaki Decision Document (PDF)(22 pp, 1.7 MB, About PDF)
Cry9C in event CBH 351
(PC code: 006466)
Corn1998Canceled (2001)Starlink™ Corn Regulatory Information
Cry1F in event TC1507
(PC code: 006481)
Corn2001ActiveCry1Ab and Cry1F Bacillus thuringiensis (Bt) Corn Plant-Incorporated Protectant (PDF)(253 pp, 1.3 MB, About PDF)
Cry3Bb1 in event MON 863
(PC code: 006484)
Corn2003Canceled
(2010)
Bacillus thuringiensis Cry3Bb1 Protein and the Genetic Material Necessary for Its Production (Vector PV-ZMIR13L) in MON 863 Corn (PDF)(234 pp, 978 K, About PDF)
moCry1F in event DAS-06275-8
(PC code: 006491)
Corn2005ActiveCry1Ab and Cry1F Bacillus thuringiensis (Bt) Corn Plant-Incorporated Protectants (PDF)(253 pp, 1.3 MB, About PDF)
Cry34/35 in event 59122-7
(PC code: 006490)
Corn2005ActiveBacillus thuringiensis Cry34Ab1 and Cry35Ab1 Proteins and the Genetic Material Necessary for Their Production (PHP17662 T-DNA) in Event DAS-59122-7 Corn (OECD Unique Identifier: DAS-59122-7) (PDF)(205 pp, 1.2 MB, About PDF)
Cry3Bb1 in event MON 88017
(PC code: 006498)
Corn2005ActiveBacillus thuringiensis Cry3Bb1 Protein and the Genetic Material Necessary for Its Production (Vector
PV-ZMIR39) in MON 88017 Corn (OECD Unique Identifier: MON-88Ø17-3) (PDF)(234 pp, 978 K, About PDF)
mCry3A in Event MIR 604
(PC code: 006509)
Corn2006ActiveModified Cry3A Protein and the Genetic Material Necessary for its Production (Via Elements of pZM26) in Event MIR604 Corn SYN-IR604-8 (PDF)(141 pp, 578 K, About PDF)
Cry1A.105 in event MON 89034
(PC code: 006514)
Corn2008ActiveBacillus thuringiensis Cry1A.105 and Cry2Ab2 Insecticidal Proteins and the Genetic Material Necessary for Their Production in Corn [PC Codes 006515 (Cry2Ab2), 006514 (Cry1A.105)] (PDF)(166 pp, 826 K, About PDF)
Cry2Bb2 in event MON 89034
(PC code: 006515)
Corn2008ActiveBacillus thuringiensis Cry1A.105 and Cry2Ab2 Insecticidal Proteins and the Genetic Material Necessary for Their Production in Corn [PC Codes 006515 (Cry2Ab2), 006514 (Cry1A.105)] (PDF)(166 pp, 826 K, About PDF)
Vip3Aa20 in event MIR 162
(PC code: 006599)
Corn2008ActiveBacillus thuringiensis Vip3Aa20 Insecticidal Protein and the Genetic Material Necessary for Its Production (via Elements of Vector pNOV1300) in Event MIR162 Maize (OECD Unique Identifier: SYN-IR162-4) (PDF)(175 pp, 784 K, About PDF)
eCry3.1Ab in event 5307
(PC code: 016483)
Corn2012ActiveDraft Biopesticides Registration Action Document Bacillus thuringiensis eCry3.1Ab Insecticidal Protein and Genetic Material
Cry3Bb1 in event MON 87411
(PC code: 006580)
Corn2015ActiveRegistration Decision for the New Active Ingredients Double-stranded Ribonucleic Acid Transcript Comprising a DvSnj7 Inverted Repeat Sequence Derived from Western Corn Rootworm (Diabrotica virgifera virgifera) and Bacillus thuringiensis Cry3Bbl Protein and the Genetic Material (vector PV-ZMIR10871) Necessary for Their Production in MON 87411 Corn (OECD Unique Identifier: MON-87411-9) 
DvSnf7 in event MON 87411
(PC code: 006566)
Corn2015ActiveRegistration Decision for Commercial Use Corn Products Containing the DvSnf7 dsRNA Plant-Incorporated - Protectant (Event MON 87411)
Cry1Ac in event MON 531
(PC code: 006445
Cotton1995ActiveBiopesticides Registration Action Document - Bacillus thuringiensis Plant-Incorporated Protectants
Cry1Ac in event MON 15985
(PC code:  006445)
Cotton2002ActiveBacillus thuringiensis Cry2Ab2 protein and its genetic material necessary for its production in cotton(75 pp, 775 K, About PDF)
Cry2Ab2 in event MON 15985
(PC code 006487)
Cotton2002ActiveBacillus thuringiensis Cry2Ab2 protein and its genetic material necessary for its production in cotton(75 pp, 775 K, About PDF)
Cry1F in event DAS-21023-5
(PC code:  006512)
Cotton2004Active(Bacillus thuringiensis var. Aizawai CRY1F and the Genetic Material (from the insert of Plasmid PGMA281) Necessary for Its Production in Cotton and Bacillus thuringiensis var. Kurstaki CRY1AC and the Genetic Material (from the insert of plasmid PMYC3006) necessary for its production in cotton)(93 pp, 571 K, About PDF)
Cry1Ac in event DAS-24236-5
(PC code:  006513)
Cotton2004Active(Bacillus thuringiensis var. Aizawai CRY1F and the Genetic Material (from the insert of Plasmid PGMA281) Necessary for Its Production in Cotton and Bacillus thuringiensis var. Kurstaki CRY1AC and the Genetic Material (from the insert of plasmid PMYC3006) necessary for its production in cotton)(93 pp, 571 K, About PDF)
Vip3Aa19 in event COT102
(PC code:  016484)
Cotton2008ActiveBacillus thuringiensis modified Cry1Ab (SYN-IR67B-1) and Vip3Aa19 (SYN-IR102-7) insecticidal proteins and the genetic material necessary for their production in COT102 X COT67B cotton(135 pp, 2.2 MB, About PDF)
FLCry1Ab in event COT67B
(PC code:  016486)
Cotton2008ActiveBacillus thuringiensis modified Cry1Ab (SYN-IR67B-1) and Vip3Aa19 (SYN-IR102-7) insecticidal proteins and the genetic material necessary for their production in COT102 X COT67B cotton(135 pp, 2.2 MB, About PDF)
Cry1Ab in event T304-40
(PC code:  006525)
Cotton2012ActiveBacillus thuringiensis Cry1Ab protein and the Genetic Material Necessary for its Production in Event T304-40 Cotton [PC Code 006525, OECD Unique Identifier: BCS-GHØØ4-7]
Cry2Ae in event GHB119
(PC code:  006600)
Cotton2012ActiveBacillus thuringiensis Cry2Ae protein and the Genetic Material Necessary for its Production in Event GHB119 Cotton [PC Code 006600, OECD Unique Identifier: BCS-GHØØ5-8]
Cry1Ac in event MON 87701
(PC code: 006532)
Soybean2010ActiveBacillus thuringiensis Cry1Ac Protein and the Genetic Material (Vector PV-GMIR9) Necessary
for Its Production in MON 87701 (OECD Unique Identifier: MON 877Ø1-2) Soybean (PDF)(39 197, yy K, About PDF)
Cry1Ac in event DAS 81419 (PC code: 006527)Soybean2014ActiveBacillus thuringiensis Cry1Ac Protein and the Genetic Material Necessary for its Production [PC Code 006527] and Bacillus thuringiensis Cry1F Protein and the Genetic Material Necessary for its Production [PC Code 006528]
Cry1F in event DAS 81419 (PC code: 006528)Soybean2014ActiveBacillus thuringiensis Cry1Ac Protein and the Genetic Material Necessary for its Production [PC Code 006527] and Bacillus thuringiensis Cry1F Protein and the Genetic Material Necessary for its Production [PC Code 006528]
Cry1A.105 in event MON 87751
(PC code: 006614
Soybean2015ActivePlant-Incorporated Protectants Bacillus Thuringiensis Cry1A.105 and Cry2Ab2 Proteins and the Genetic Material (Vector PV-GMIR13196) Necessary For Their Production in MON 87751 (OECD Unique ID. MON-87751-7) Soybean [PC Code 006614 and PC Code 006527]
Cry2Ab2 in event MON 87751
(PC code: 006615)
Soybean2015ActivePlant-Incorporated Protectants Bacillus Thuringiensis Cry1A.105 and Cry2Ab2 Proteins and the Genetic Material (Vector PV-GMIR13196) Necessary For Their Production in MON 87751 (OECD Unique ID. MON-87751-7) Soybean [PC Code 006614 and PC Code 006527]
Cry3A in New Leaf Potato
(PC code: 006432)
Potato1995ActiveBiopesticides Registration Action DocumentBacillus thuringiensis Plant-Incorporated Protectants
Replicase for potato leaf roll virus
(PC code: 006469
Potato1998ActivePotato Leaf Roll Virus Resistance Gene (also known as orf1/orf2 gene) (006469) Registration Eligibility Document (PDF)(19 pp, 71 K, About PDF)
C5 Honeysweet plum (plum pox viral coat protein gene)
(PC code: 006354)
Plum2010ActiveCoat Protein Gene of Plum Pox Virus (PDF)(30 pp, 288 K, About PDF)
X17-2 papaya (ringspot virus resistance gene)
(PC code: 006701)
Papaya2016ActiveProposed Registration Decision for the New Active Ingredient Papaya Ringspot Virus Resistance Gene (Papaya Ringspot Virus Coat Protein Gene) in Xl7-2 Papaya (OECD Unique Identifier: UFL-Xl7CP-6)

1BRAD = Biopesticide Registration Action Document, a summary of the risk assessments and regulatory decisions for each registered PIP active ingredient

Resources

  • Plant Incorporated Protectants (PIPs)
  • PIP labels and regulatory approvals via PPLS by entering the EPA registration number
  • 2010 Bt Corn Reregistration Terms & Conditions
  • PIP risk assessments and dockets via ChemSearch by entering the PC Code
  • Petitions for Determination of Non-regulated Status USDA-APHIS (United States Department of Agriculture)
  • Biotechnology Consultations on Food from GE Plant Varieties FDA (Food and Drug Administration) 
  • FAO (United Nations Food and Agriculture Organization) GM Foods Platform: Information using the corresponding OECD unique identifier
  • List of biopesticide active ingredients
Contact Us about Ingredients Used in Pesticide Products to ask a question, provide feedback, or report a problem.
Last updated on July 11, 2025
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