Endocrine Disruptor Screening Program Tier 1 Screening Determinations and Associated Data Evaluation Records

The table below contains a collection of documents that present Endocrine Disruptor Screening Program (EDSP) Tier 1 Screening determinations (or weight-of-evidence (WoE) assessments) and associated data evaluation records (DERs) for 52 Tier 1 chemicals as of September 23, 2015. EPA is recommending additional testing, known as Tier 2 testing, for 18 chemicals highlighted in green in the table. View the additional tests required for each chemical.

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Chemical NameCAS NumberDocket NumberEDSP Tier 1 Screening Determinations/WoE AssessmentsAssociated Data Evaluation Records (DERs)
2,4-D94-75-7EPA-HQ-OPP-2012-0330 2,4-D EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF) (221 pp, 6,644 K, About PDF)2,4-D: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(221 pp, 6,489 K, About PDF)
Abamectin71751-41-2EPA-HQ-OPP-2013-0360Abamectin EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(61 pp, 1,013y K, About PDF)Abamectin: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(252 pp, 8,541  K, About PDF)
Acephate30560-19-1EPA-HQ-OPP-2008-0915Acephate EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(59 pp, 1,006 K, About PDF)Acephate: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(283 pp, 8,219 K, About PDF)
Acetone67-64-1EPA-HQ-OPP-2009-0634Acetone EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(41 pp, 907 K, About PDF)Acetone: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(237 pp, 8,504 K, About PDF)
Atrazine1912-24-9EPA-HQ-OPP-2013-0266Atrazine EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(167 pp, 1,572 K, About PDF)Atrazine: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(59 pp, 1,083 K, About PDF)
Benfluralin1861-40-1EPA-HQ-OPP-2011-0931Benfluralin EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(61 pp, 1,025 K, About PDF)Benfluralin: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(300 pp, 7,995 K, About PDF)
Bifenthrin82657-04-3EPA-HQ-OPP-2010-0384Bifenthrin EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(67pp, 1,051 K, About PDF)Bifenthrin: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(320 pp, 8,542 K, About PDF)
Captan133-06-2EPA-HQ-OPP-2013-0296Captan EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(59 pp, 1,011 K, About PDF)Captan: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(303 pp, 9,027 K, About PDF)
Carbaryl63-25-2EPA-HQ-OPP-2010-0230Carbaryl EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(70 pp, 1,041 K, About PDF)Carbaryl: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(149 pp, 5,716 K, About PDF)
Carbofuran1563-66-2EPA-HQ-OPP-2009-0634Carbofuran EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(237 pp, 8,707 K, About PDF)Carbofuran: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(260 pp, 8,707 K, About PDF)
Chlorothalonil1897-45-6EPA-HQ-OPP-2011-0840Chlorothalonil EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(69 pp, 1,056 K, About PDF)Chlorothalonil: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(260 pp, 10,213K,  About PDF)
Chlorpyrifos2921-88-2EPA-HQ-OPP-2008-0850Chlorpyrifos EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(82 pp, 1,116 K, About PDF)Chlorpyrifos: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(289 pp, 8,319 K, About PDF)
Cyfluthrin68359-37-5EPA-HQ-OPP-2010-0684Cyfluthrin EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(76 pp, 1,111 K, About PDF)Cyfluthrin: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(285 pp, 1,0326 K, About PDF)
Cypermethrin52315-07-8EPA-HQ-OPP-2012-0167Cypermethrin EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(72 pp, 1,095 K, About PDF)Cypermethrin: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(223 pp, 5,244y K, About PDF)
DCPA1861-32-1EPA-HQ-OPP-2011-0374DCPA EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(52 pp, 963 K, About PDF)DCPA: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(321 pp, 9.951 K, About PDF)
Diazinon333-41-5EPA-HQ-OPP-2008-0351Diazinon EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(71 pp, 1,062 K, About PDF)Diazinon: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(281 pp, 8,365 K, About PDF)
Dichlobenil1194-65-6EPA-HQ-OPP-2012-0395Dichlobenil EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(60 pp, 1,042 K, About PDF)Dichlobenil: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(331 pp,7,294 K, About PDF)
Dimethoate60-51-5EPA-HQ-OPP-2009-0059-Dimethoate EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(71 pp, 1,117 K, About PDF)Dimethoate: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(225 pp, 6,327 K, About PDF)
EPTC759-94-4EPA-HQ-OPP-2012-0720EPTC EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(63 1,022, K, About PDF)EPTC: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(310 pp, 7,136 K, About PDF)
Esfenvalerate66230-04-4EPA-HQ-OPP-2009-0301Esfenvalerate EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(70 pp, 1,042 K, About PDF)Esfenvalerate: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(206 pp, 8,882 K, About PDF)
Ethoprop13194-48-4EPA-HQ-OPP-2008-0560Ethoprop EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(67 pp, 1,000 K, About PDF)Ethoprop: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(258 pp, 11,504 K, About PDF)
Fenbutatin oxide13356-08-6EPA-HQ-OPP-2009-0841Fenbutatin oxide EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(54 pp, 960 K, About PDF)Fenbutatin oxide: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(287 pp, 11,479 K, About PDF)
Flutolanil66332-96-5EPA-HQ-OPP-2008-0148Flutolanil EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(56 pp, 954 K, About PDF)Flutolanil: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(270 pp, 9,039 K, About PDF)
Folpet133-07-3EPA-HQ-OPP-2012-0859Folpet EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(56 pp, 962 K, About PDF)Folpet: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(311 pp, 10,459 K, About PDF)
Gardona (cis-isomer) / Tetrachlorvinphos22248-79-9EPA-HQ-OPP-2008-0316Gardona (cis-isomer) / Tetrachlorvinphos EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(66 pp, 1,014 K, About PDF)Gardona (cis-isomer) / Tetrachlorvinphos: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(263 pp, 45,80 K, About PDF)
Glyphosate1071-83-6EPA-HQ-OPP-2009-0361Glyphosate EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(70 pp, 1042 K, About PDF)Glyphosate: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(278 pp, 10,390 K, About PDF)
Imidacloprid138261-41-3EPA-HQ-OPP-2008-0844Imidacloprid EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(70 pp, 1,021 K, About PDF)Imidacloprid: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(273 pp, 9,834 K, About PDF)
Iprodione36734-19-7EPA-HQ-OPP-2012-0392Iprodione EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(74 pp, 1,039 K, About PDF)Iprodione: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(211 pp, 4,138 K, About PDF)
Isophorone78-59-1EPA-HQ-OPP-2009-0634Isophorone EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(51 pp, 886 K, About PDF)Isophorone: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(308 pp, 10,150 K, About PDF)
Linuron330-55-2EPA-HQ-OPP-2010-0228Linuron EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(101 pp, 1,158 K, About PDF)Linuron: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(124 pp, 4,903 K, About PDF)
Malathion121-75-5EPA-HQ-OPP-2009-0317Malathion EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(82 pp, 1,144 K, About PDF)Malathion: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(294 pp, 5,265 K, About PDF)
Metalaxyl57837-19-1EPA-HQ-OPP-2009-0863Metalaxyl EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(59 pp, 992 K, About PDF)Metalaxyl: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(292 pp, 4,096 K, About PDF)
Methomyl16752-77-5EPA-HQ-OPP-2010-0751Methomyl EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(62 pp, 1,023 K, About PDF)Methomyl: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(241 pp, 5,649 K, About PDF)
Metolachlor51218-45-2EPA-HQ-OPP-2014-0772Metolachlor EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(69 pp, 1,039 K, About PDF)Metolachlor: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(288 pp, 3,993 K, About PDF)
Metribuzin21087-64-9EPA-HQ-OPP-2012-0487Metribuzin EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(57 pp, 976 K, About PDF)Metribuzin: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(205 pp, 3,083 K, About PDF)
MGK 264113-48-4EPA-HQ-OPP-2012-0415MGK 264 EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(57, 984 K, About PDF)MGK 264: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(242 pp, 9,430 K, About PDF)
Myclobutanil88671-89-0EPA-HQ-OPP-2015-0053Myclobutanil EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(65 pp, 1,030 K, About PDF)Myclobutanil: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(317 pp, 9,239 K, About PDF)
Norflurazon27314-13-2EPA-HQ-OPP-2012-0565Norflurazon EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(62 pp, 1,013 K, About PDF)Norflurazon: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(344 pp, 10,343 K, About PDF)
O-phenylphenol90-43-7EPA-HQ-OPP-2013-0524O-phenylphenol EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(64 pp, 1,011 K, About PDF)O-phenylphenol: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(281 pp, 7,933 K, About PDF)
Oxamyl23135-22-0EPA-HQ-OPP-2010-0028Oxamyl EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(56 pp, 962 K, About PDF)Oxamyl: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(241 pp, 9,604 K, About PDF)
PCNB82-68-8EPA-HQ-OPP-2009-0634PCNB EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(70 pp, 1,064 K, About PDF)PCNB: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(207 pp, 4,452 K, About PDF)
Permethrin52645-53-1EPA-HQ-OPP-2011-0039Permethrin EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(75 pp, 1,093 K, About PDF)Permethrin: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(206 pp, 3,685 K, About PDF)
Phosmet732-11-6EPA-HQ-OPP-2009-0316Phosmet EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(3 pp, 704 K, About PDF)Phosmet: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(260 pp, 5,676 K, About PDF)
Piperonyl butoxide51-03-6EPA-HQ-OPP-2010-0498Piperonyl butoxide EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(62 pp, 972 K, About PDF)Piperonyl butoxide: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(252 pp, 5,544 K, About PDF)
Propargite2312-35-8EPA-HQ-OPP-2014-0131Propargite EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(3 pp, 599 K, About PDF)Propargite: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(307 pp, 9,225 K, About PDF)
Propiconazole60207-90-1EPA-HQ-OPP-2009-0634Propiconazole EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(87pp, 1,113 K, About PDF)Propiconazole: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(154 pp, 4,108 K, About PDF)
Propyzamide23950-58-5EPA-HQ-OPP-2009-0326Propyzamide EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(75 pp, 1,108 K, About PDF)Propyzamide: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(285 8,102 K, About PDF)
Pyriproxyfen95737-68-1EPA-HQ-OPP-2011-0677Pyriproxyfen EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(41 pp, 8,852 K, About PDF)Pyriproxyfen: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)281 pp, 9,364 K, About PDF)
Simazine122-34-9EPA-HQ-OPP-2013-0251Simazine EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(74 pp, 1,108 K, About PDF)Simazine: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(196 pp, 4,504 K, About PDF)
Tebuconazole107534-96-3EPA-HQ-OPP-2015-0634Tebuconazole EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(89 pp, 1,181 K, About PDF)Tebuconazole: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(237 pp, 2,842 K, About PDF)
Triadimefon43121-43-3EPA-HQ-OPP-0258Triadimefon EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(69pp, 1,033 K, About PDF)Triadimefon: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(144 pp, 2,621 K, About PDF)
Trifluralin1582-09-8EPA-HQ-OPP-2012-0417Trifluralin EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays (PDF)(66 pp, 1,071 K, About PDF)Trifluralin: Data Evaluation Records (DERs) for EDSP Tier 1 Assays (PDF)(304 pp, 4,864 K, About PDF)

Final decisions will be made for these chemicals in regard to the need of Tier 2 tests as detailed in the OIG Report.

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