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FIFRA Scientific Advisory Panel Members

Members are appointed by the Administrator of EPA from nominations provided by the National Institutes of Health (NIH) and the National Science Foundation (NSF). Members serve staggered terms of appointment, generally of three years duration. Current FIFRA SAP panel members are listed below.

The comment period for nominees to the SAP has closed. View biographical sketches for the nominees.

Chair

  • Robert E. Chapin, Ph.D.
    Former Senior Research Fellow, (Retired)
    Pfizer Global Research and Development, Groton, CT

    Education

    Ph.D., Pharmacology, University of North Carolina, Chapel Hill; B.A., Biology, Earlham College

    Biographical Sketch

    Dr. Robert Chapin has recently retired from his position as a Senior Research Fellow and member of the Developmental and Reproductive Toxicology Center of Expertise at Pfizer Global Research and Development in Groton, Connecticut. He received his Ph.D. degree in 1980 from UNC-Chapel Hill in Pharmacology and subsequently post-doctored for 2 years at the Chemical Industry Institute of Toxicology. This was followed by 18 years at the National Institute of Environmental Health Sciences (NIEHS), as a Senior Staff Fellow in the National Toxicology Program, then as a Principal Investigator, and then Lab Head. His area of expertise is pre-conception reproductive toxicology in male and female; however, he also worked hard in the area of in vitro predictive toxicology. He developed advanced in vitro culture methods for exploring mechanisms of reproductive toxicology and helped pioneer the integrated use of molecular, biochemical, histologic, and in vitro methods to address mechanistic questions in reproductive toxicology.

Members

  • George B. Corcoran, Ph.D.
    Chairman and Professor, Department of Pharmaceutical Sciences
    Wayne State University, Detroit, MI

    Education

    Ph.D., Pharmacology/Toxicology, George Washington University; M.S., Chemistry, Bucknell University; B.A., Chemistry, Ithaca College

    Biographical Sketch

    Dr. Corcoran is a Professor and Chairman of the Department of Pharmaceutical Sciences, College of Pharmacy & Health Sciences, Wayne State University, and Adjunct Professor of Pediatrics, Wayne State University School of Medicine. Prior to Wayne State, Dr. Corcoran served as Assistant Professor of Pharmaceutics at the State University of New York at Buffalo and Associate Professor, and later Professor and Director of the Toxicology Graduate Program at the University of New Mexico. Dr. Corcoran has served as Secretary and later President of the Society of Toxicology. His research interests are multidisciplinary and translational. They focus on cellular injury and cell death, and factors that govern drug and chemical injuries, including drug metabolism and nutrition.

  • Rebecca Klaper, Ph.D.
    Professor, School of Freshwater Sciences
    University of Wisconsin-Milwaukee, Milwaukee, WI

    Education

    Ph.D., Ecology; MS, Entomology, Institute of Ecology, University of Georgia

    Biographical Sketch

    Dr. Rebecca D. Klaper is a Professor at the School of Freshwater Sciences, University of Wisconsin-Milwaukee and the Director of the Great Lakes Genomics Center. Dr. Klaper received her MS in Entomology in 1995 and her Ph.D. in Ecology in 2000 from the Institute of Ecology University of Georgia examining the impacts of chemicals on the population dynamics of insects.

    Dr. Klaper currently studies the potential impact of emerging contaminants, such as nanoparticles, pharmaceuticals, personal care products and pesticides on aquatic life and how we may design these chemicals to be sustainable and have the least environmental impact. She published some of the first studies on the impacts of nanomaterials on aquatic organisms, describing differences in toxicity among nanomaterials, discussing the possible impacts of surfactants on nanomaterial toxicology. Dr. Klaper is now one of the lead PI's for the Center for Sustainable Nanotechnology, a distributed Center of eight universities to evaluate the mechanisms by which nanomaterials may cause toxicity and investigate the potential for principles to use in the design process of these chemicals.

    Dr. Klaper received a AAAS-Science and Technology Policy Fellowship where she worked in the National Center for Environmental Assessment at the US Environmental Protection Agency evaluating the potential use of genomic technologies in risk assessment. She is also on the editorial board of the SETAC journal Environmental Toxicology and Chemistry as well as the ACS journal Chemical Research in Toxicology. Her current research focuses on (1) determining the presence of contaminants in freshwater systems; (2) the impacts of low level chronic exposures of these chemicals to fish and invertebrates in freshwater systems; (3) evaluating the ability of contaminant removal technologies to remove biological impacts of chemicals; (4) methods to quickly assess the potential impacts of a chemical, including genomic technologies; and (5) alternative options for minimizing the impacts of emerging contaminants including chemical redesign and Green Chemistry, altering use and distribution, and evaluating prescription levels for pharmaceuticals. Dr. Klaper's goal is to conduct basic and applied research to inform policy decisions involving freshwater resources.

  • Joseph R. Shaw, Ph.D.
    Associate Professor, School of Public Health and Environmental Affairs, Indiana University Adjunct Appointments, School of Public Health and Center for Genomics and Bioinformatics Indiana University, Bloomington, IN

    Education

    Ph.D., Environmental Toxicology, University of Kentucky

    Biographical Sketch

    Dr. Joseph R. Shaw is an Associate Professor in the School of Public and Environmental Affairs at Indiana University and holds adjunct appointments in their School of Public Health and Center for Genomics and Bioinformatics. He also holds a partial appointment as a Senior Lecturer of Environmental Genomics in the School of Biosciences at the University of Birmingham, UK. Dr. Shaw earned his doctoral degree in environmental toxicology from the Graduate Center for Toxicology at the University of Kentucky in 2001.

    He then moved to Dartmouth College where he received an National Institute of Environmental Health Sciences (NIEHS) post-doctoral fellowship to apply emerging Omics technologies to characterize mechanisms of toxicant actions. He joined the faculty of the School of Public and Environmental Affairs at Indiana University, Bloomington in 2007. Dr. Shaw was named an Outstanding New Environmental Scientist (ONES) by the NIEHS in 2010, and recognized as an exceptional talent in the environmental sciences by the Royal Society, UK in 2013 for his work investigating toxicant exposure, genome structure, and toxic effects on individuals and populations. His research group seeks to discover critical, specific, and causative molecular toxicological and disease pathways resulting from complex environmental exposures. His work embraces new high- throughput molecular techniques and couples these with evolutionary theory, statistical analysis, and bioinformatics to integrate toxic-response across levels of biological organization. Current research in his laboratory focuses on: (1) associating variation in genome structure with disease and toxicant response within and between populations; (2) identifying the mechanisms of actions of chemical stress, especially metals; and (3) elucidating the genetic and epigenetic underpinnings of mutations and establishing their role in evolved tolerance.

  • Sonya K. Sobrian, Ph.D.
    Associate Professor, Department of Pharmacology, Howard University College of Medicine Director, Developmental Neurobehavioral Pharmacology Laboratory Howard University, Washington, DC

    Education

    Ph.D., Physiological Psychology, Carleton University, Ottawa Canada; MA, Neuropharmacology, Ottawa University, Canada

    Biographical Sketch

    Dr. Sonya K. Sobrian is an Associate Professor of Pharmacology at the Howard University College of Medicine, Director of the Developmental Neurobehavioral Pharmacology Laboratory, and Past Chair of the University's Institutional Animal Care and Use Committee (IACUC). Dr. Sobrian received her doctorate in Physiological Psychology from Carleton University, Ottawa Canada, and served a postdoctoral fellowship at Princeton University in Developmental Neurobiology. She also added pharmacology and immunology to her graduate (MA, Neuropharmacology, Ottawa University) and post graduate (Fulbright Fellow: Immunology Research Center, Belgrade, Yugoslavia) training.

    The major focus of Dr. Sobrian's research involves the behavioral, immunological, and neurotoxicological consequences of prenatal and neonatal drug administration and drug and environmental stress-induced alterations in behavioral and immunological development. She has a longstanding interest in sex differences, and her lab was the first to show that prenatal environmental and psychological stress deferentially altered immune parameters in rat male and female offspring, research that she continued as a Fulbright Scholar at the Immunological Research Institute in Belgrade, Yugoslavia.

    Previous research has focused on the life-span consequences of prenatal exposure to cocaine and nicotine, alone and in combination, with an emphasis on drug addiction in the aging organism. As a visiting scientist at the National Center for Toxicological Research, in Arkansas, Dr. Sobrian was instrumental in establishing a prenatal model of cocaine toxicity. Dr. Sobrian is also exploring the role of prenatal environmental noise stress (PENS) in the etiology of autism and depression. For her work in establishing an environmentally-mediated neurodevelopmental animal model of depression, Dr. Sobrian was designated a L. Vernon Maddox National Alliance for Research in Schizophrenia and Affective Disorders (NARSAD) investigator. Currently her research involves the multi- and trans- generational inheritance of addiction-like behaviors following prenatal exposure to synthetic cannabinoids.

    Dr. Sobrian has served as Director of the Behavioral Neuroscience Program at the National Science Foundation, Chair of the Board of Directors of the National Capital Area Chapter of the Fulbright Association, and Chair of the Board of Trustees of the Association for Assessment and Accreditation of Laboratory Animal Care (AAALAC) International. She has been President of the Developmental Neurotoxicology Society [formerly Neurobehavioral Teratology Society], and currently serves as Section Editor for Developmental Toxicology of that society’s scientific journal, Neuroteratology and Toxicology. Dr. Sobrian was formerly on the Board of Scientific Counselors for the Department of Health & Human Services National Toxicology Program.

    She is the Developmental Toxicology section editors of the journal Neurotoxicology and Teratology.

  • Clifford P. Weisel, Ph.D.
    Professor
    Rutgers University, Piscataway, NJ

    Education

    Ph.D., Chemical Oceanography, University of Rhode Island; M.S., Analytical Chemical, University of Rhode Island; B.S., Chemistry, State University of New York at Stony Brook

    Biographical Sketch

    Dr. Clifford Weisel is a Professor at Rutgers University and a member of the Exposure Science and Epidemiology Division of the Environmental and Occupational Health Sciences Institute. He is Director of the Doctoral Degree Program in Exposure Science offered by Rutgers University. Dr. Weisel's research focuses on understanding exposure to chemical agents, with an emphasis on multi-route exposures to environmental contaminants, the association between exposure and adverse health effects, utilization of sensors for continuous exposure measurement, and development and application of biomarkers of exposure. He has examined the relationship among indoor, outdoor and personal exposures to air pollutants; documented the importance of inhalation and dermal exposure to contaminants; characterized exposures within the transportation sector; and examined exposure and health issues related to disinfection by-products in water. Dr. Weisel is past President (2007-2008) and Treasurer (2000-2003) of the International Society of Exposure Science (ISES).

  • Raymond S.H. Yang, Ph.D.
    Professor (Emeritus), College of Veterinary Medicine and Biomedical Sciences
    Colorado State University, Fort Collins, CO

    Education

    Ph.D., Toxicology/Entomology, North Carolina State University; B.S., Biology, National Taiwan University

    Biographical Sketch

    Dr. Raymond Yang is Professor Emeritus of Toxicology and Cancer Biology at the College of Veterinary Medicine and Biomedical Sciences, Colorado State University (CSU). Currently, Dr. Yang works part-time as an International Consultant. Part of his services includes the teaching of a “PBPK Modeling Workshop for Beginners” at CSU and elsewhere in the US, Europe, and Asia. Dr. Yang’s research interests focus on physiologically-based pharmacokinetic/ pharmacodynamic (PBPK/PD) modeling, and other biologically-based computer modeling with a special emphasis on the toxicology and risk or safety assessment of chemical mixtures, poly-pharmacy, and multiple stressors, including radiation. Dr. Yang has had extensive research and administrative experience in academia, chemical industry, and the federal government and is a Fellow of the Academy of Toxicological Sciences.