FIFRA Scientific Advisory Panel Members
Members are appointed by the Administrator of EPA from nominations provided by the National Institutes of Health (NIH) and the National Science Foundation (NSF). Members serve staggered terms of appointment, generally of three years duration. Current FIFRA SAP panel members are listed below.
The comment period for nominees to the SAP has closed. View biographical sketches for the nominees.
- Robert E. Chapin, Ph.D.
(Retired) Pfizer Global Research and Development
Affiliation: Former Senior Research Fellow (Retired), Pfizer Global Research and Development, Groton, CT
Expertise: In vitro predictive toxicology; pre-conception reproductive toxicology
Education: Ph.D., Pharmacology, University of North Carolina, Chapel Hill; B.A., Biology, Earlham College
Experience Summary: Dr. Robert Chapin has recently retired from his position as a Senior Research Fellow and member of the Developmental and Reproductive Toxicology Center of Expertise at Pfizer Global Research and Development in Groton, Connecticut. He received his Ph.D. degree in 1980 from UNC-Chapel Hill in Pharmacology and subsequently post-doctored for 2 years at the Chemical Industry Institute of Toxicology. This was followed by 18 years at the National Institute of Environmental Health Sciences (NIEHS), as a Senior Staff Fellow in the National Toxicology Program, then as a Principal Investigator, and then Lab Head. His area of expertise is pre-conception reproductive toxicology in male and female; however, he also worked hard in the area of in vitro predictive toxicology. He developed advanced in vitro culture methods for exploring mechanisms of reproductive toxicology and helped pioneer the integrated use of molecular, biochemical, histologic, and in vitro methods to address mechanistic questions in reproductive toxicology.
Panel Experience: Dr. Chapin has served as an ad hoc member on several Scientific Advisory Panels for the U.S. Environmental Protection Agency (U.S. EPA) specifically the National Research Council’s Low Dose Non-Monotone Panel (2013), and had previously worked on numerous International Life Sciences Institute committees and publications (2009-2011). Dr. Chapin currently serves as Chair of the Federal Insecticide, Fungicide, and Rodenticide Act Scientific Advisory Panel (2018-2021).
- George B. Corcoran, Ph.D.
Wayne State University
Affiliation: Chairman and Professor, Department of Pharmaceutical Sciences, Wayne State University, Detroit, MI
Expertise: Cellular injury; cell death and factors that govern drug and chemical injuries, including drug metabolism and nutrition
Education: Ph.D., Pharmacology/Toxicology, George Washington University; M.S., Chemistry, Bucknell University; B.A., Chemistry, Ithaca College
Experience Summary: Dr. Corcoran is a Professor and Chairman of the Department of Pharmaceutical Sciences, College of Pharmacy & Health Sciences, Wayne State University, and Adjunct Professor of Pediatrics, Wayne State University School of Medicine. Prior to Wayne State, Dr. Corcoran served as Assistant Professor of Pharmaceutics at the State University of New York at Buffalo and Associate Professor, and later Professor and Director of the Toxicology Graduate Program at the University of New Mexico. Dr. Corcoran has served as Secretary and later President of the Society of Toxicology. His research interests are multidisciplinary and translational. They focus on cellular injury and cell death, and factors that govern drug and chemical injuries, including drug metabolism and nutrition.
Panel Experience: Dr. Corcoran has served on and/or chaired review panels for the National Institutes of Health (1996-2002), the National Academies (2000-2005), and the Howard Hughes Medical Institute (2000-2003). He is a past Member of the Scientific Advisory Board of the U.S. EPA (2003-2009), Past Chair (2012-2013) of the Executive Board of the Council of Scientific Society Presidents (2007-2013), and past member of the Inter-Governmental Scientific Advisory Committee on Alternative Toxicological Methods (2008-2011). Dr. Corcoran is currently a member of the Federal Insecticide, Fungicide, and Rodenticide Act Scientific Advisory Panel (2018-2021).
- Rebecca Klaper, Ph.D.
University of Wisconsin-Milwaukee
Affiliation: Professor, School of Freshwater Sciences, University of Wisconsin-Milwaukee, Milwaukee, WI
Expertise: Chemical Engineering; Ecotoxicology; Genomics
Education: Ph.D., Ecology; MS, Entomology, Institute of Ecology, University of Georgia
Experience Summary: Dr. Rebecca D. Klaper is a Professor at the School of Freshwater Sciences, University of Wisconsin-Milwaukee and the Director of the Great Lakes Genomics Center. Dr. Klaper received her MS in Entomology in 1995 and her Ph.D. in Ecology in 2000 from the Institute of Ecology University of Georgia examining the impacts of chemicals on the population dynamics of insects.
Dr. Klaper currently studies the potential impact of emerging contaminants, such as nanoparticles, pharmaceuticals, personal care products and pesticides on aquatic life and how we may design these chemicals to be sustainable and have the least environmental impact. She published some of the first studies on the impacts of nanomaterials on aquatic organisms, describing differences in toxicity among nanomaterials, discussing the possible impacts of surfactants on nanomaterial toxicology. Dr. Klaper is now one of the lead PI's for the Center for Sustainable Nanotechnology, a distributed Center of eight universities to evaluate the mechanisms by which nanomaterials may cause toxicity and investigate the potential for principles to use in the design process of these chemicals.
Dr. Klaper received a AAAS-Science and Technology Policy Fellowship where she worked in the National Center for Environmental Assessment at the US Environmental Protection Agency evaluating the potential use of genomic technologies in risk assessment. She is also on the editorial board of the SETAC journal Environmental Toxicology and Chemistry as well as the ACS journal Chemical Research in Toxicology. Her current research focuses on (1) determining the presence of contaminants in freshwater systems; (2) the impacts of low level chronic exposures of these chemicals to fish and invertebrates in freshwater systems; (3) evaluating the ability of contaminant removal technologies to remove biological impacts of chemicals; (4) methods to quickly assess the potential impacts of a chemical, including genomic technologies; and (5) alternative options for minimizing the impacts of emerging contaminants including chemical redesign and Green Chemistry, altering use and distribution, and evaluating prescription levels for pharmaceuticals. Dr. Klaper's goal is to conduct basic and applied research to inform policy decisions involving freshwater resources.
Panel Experience: Dr. Klaper has served on the Board of Scientific Counselors for the US Environmental Protection Agency's Chemical Safety for Sustainability/Human Health Risk Assessment Subcommittee (2014). She has also served on the National Academy of Sciences Panel to Develop a Research Strategy for Environmental, Health, and Safety Aspects of Engineered Nanomaterials (2009-2013). Dr. Klaper is currently a member of the Federal Insecticide, Fungicide, and Rodenticide Act Scientific Advisory Panel (2016-2019).
- Joseph R. Shaw, Ph.D.
Affiliation: Associate Professor, School of Public and Environmental Affairs, Indiana University; Adjunct Appointments, School of Public Health and Center for Genomics and Bioinformatics, Bloomington, IN
Expertise: Bioinformatics; Environmental Toxicology; Genomics; Physiology; Plant Genomics
Education: Ph.D., Environmental Toxicology, University of Kentucky
Experience Summary: Dr. Joseph R. Shaw is an Associate Professor in the School of Public and Environmental Affairs at Indiana University and holds adjunct appointments in their School of Public Health and Center for Genomics and Bioinformatics. He also holds a partial appointment as a Senior Lecturer of Environmental Genomics in the School of Biosciences at the University of Birmingham, UK. Dr. Shaw earned his doctoral degree in environmental toxicology from the Graduate Center for Toxicology at the University of Kentucky in 2001.
He then moved to Dartmouth College where he received an National Institute of Environmental Health Sciences (NIEHS) post-doctoral fellowship to apply emerging Omics technologies to characterize mechanisms of toxicant actions. He joined the faculty of the School of Public and Environmental Affairs at Indiana University, Bloomington in 2007. Dr. Shaw was named an Outstanding New Environmental Scientist (ONES) by the NIEHS in 2010, and recognized as an exceptional talent in the environmental sciences by the Royal Society, UK in 2013 for his work investigating toxicant exposure, genome structure, and toxic effects on individuals and populations. His research group seeks to discover critical, specific, and causative molecular toxicological and disease pathways resulting from complex environmental exposures. His work embraces new high- throughput molecular techniques and couples these with evolutionary theory, statistical analysis, and bioinformatics to integrate toxic-response across levels of biological organization. Current research in his laboratory focuses on: (1) associating variation in genome structure with disease and toxicant response within and between populations; (2) identifying the mechanisms of actions of chemical stress, especially metals; and (3) elucidating the genetic and epigenetic underpinnings of mutations and establishing their role in evolved tolerance.
Panel Experience: Dr. Shaw has previously served on several advisory panels to include FIFRA SAP Peer Review of Continuing Development of Alternative High-Throughput Screens to Determine Endocrine Disruption, Focusing on Androgen Receptor, Steroidogenesis, and Thyroid Pathways (2017); FIFRA SAP Review of A Set of Scientific Issues Being Evaluated by the Environmental Protection Agency (EPA) Regarding EPA's Evaluation of the Carcinogenic Potential of Glyphosate (2016); and Human Health and Ecological Risk Assessments for SmartStax PRO 2016). Dr. Shaw is currently a member of the Federal Insecticide, Fungicide, and Rodenticide Act Scientific Advisory Panel (2016-2019).
- Sonya K. Sobrian, Ph.D.
Affiliation: Associate Professor, Department of Pharmacology, Howard University College of Medicine, Developmental Neurobehavioral Pharmacology Laboratory, Howard University, Washington, DC
Expertise: Developmental Neurotoxicity; Pharmacology
Education: Ph.D., Physiological Psychology, Carleton University, Ottawa Canada; MA, Neuropharmacology, Ottawa University, Canada
Experience Summary: Dr. Sonya K. Sobrian is an Associate Professor of Pharmacology at the Howard University College of Medicine, Director of the Developmental Neurobehavioral Pharmacology Laboratory, and Past Chair of the University's Institutional Animal Care and Use Committee (IACUC). Dr. Sobrian received her doctorate in Physiological Psychology from Carleton University, Ottawa Canada, and served a postdoctoral fellowship at Princeton University in Developmental Neurobiology. She also added pharmacology and immunology to her graduate (MA, Neuropharmacology, Ottawa University) and post graduate (Fulbright Fellow: Immunology Research Center, Belgrade, Yugoslavia) training.
The major focus of Dr. Sobrian's research involves the behavioral, immunological, and neurotoxicological consequences of prenatal and neonatal drug administration and drug and environmental stress-induced alterations in behavioral and immunological development. She has a longstanding interest in sex differences, and her lab was the first to show that prenatal environmental and psychological stress deferentially altered immune parameters in rat male and female offspring, research that she continued as a Fulbright Scholar at the Immunological Research Institute in Belgrade, Yugoslavia.
Previous research has focused on the life-span consequences of prenatal exposure to cocaine and nicotine, alone and in combination, with an emphasis on drug addiction in the aging organism. As a visiting scientist at the National Center for Toxicological Research, in Arkansas, Dr. Sobrian was instrumental in establishing a prenatal model of cocaine toxicity. Dr. Sobrian is also exploring the role of prenatal environmental noise stress (PENS) in the etiology of autism and depression. For her work in establishing an environmentally-mediated neurodevelopmental animal model of depression, Dr. Sobrian was designated a L. Vernon Maddox National Alliance for Research in Schizophrenia and Affective Disorders (NARSAD) investigator. Currently her research involves the multi- and trans- generational inheritance of addiction-like behaviors following prenatal exposure to synthetic cannabinoids.
Dr. Sobrian has served as Director of the Behavioral Neuroscience Program at the National Science Foundation, Chair of the Board of Directors of the National Capital Area Chapter of the Fulbright Association, and Chair of the Board of Trustees of the Association for Assessment and Accreditation of Laboratory Animal Care (AAALAC) International. She has been President of the Developmental Neurotoxicology Society [formerly Neurobehavioral Teratology Society], and currently serves as Section Editor for Developmental Toxicology of that society’s scientific journal, Neuroteratology and Toxicology. Dr. Sobrian was formerly on the Board of Scientific Counselors for the Department of Health & Human Services National Toxicology Program.
She is the Developmental Toxicology section editors of the journal Neurotoxicology and Teratology.
Panel Experience: Dr. Sobrian has previously served on numerous FIFRA SAP advisory panels including: Chlorpyrifos - Analysis of Biomonitoring Data (2016); Evaluation of the Common Mechanism of Action of Pyrethroid Pesticides; Peer Review of Continuing Development of Alternative High-Throughput Screens to Determine Endocrine Disruption, Focusing on Androgen Receptor, Steroidogenesis, and Thyroid Pathways (2017); Review of A Set of Scientific Issues Being Evaluated by the Environmental Protection Agency (EPA) Regarding EPA's Evaluation of the Carcinogenic Potential of Glyphosate (2016); Human Health and Ecological Risk Assessments for SmartStax PRO (2016); Comparative Toxicity Sensitivity of Adults and Juveniles to Pyrethroids (2010). Dr. Sobrian is currently a member of the Federal Insecticide, Fungicide, and Rodenticide Act Scientific Advisory Panel (2016-2019).
- Clifford P. Weisel, Ph.D.
Affiliation: Professor, Rutgers University, Piscataway, New Jersey
Expertise: Exposures to chemical agents; multi-route exposures to environmental contaminants; the association between exposure and adverse health effects; utilization of sensors for continuous exposure measurement; and development and application of biomarkers of exposure
Education: Ph.D., Chemical Oceanography, University of Rhode Island; M.S., Analytical Chemical, University of Rhode Island; B.S., Chemistry, State University of New York at Stony Brook
Experience Summary: Dr. Clifford Weisel is a Professor at Rutgers University and a member of the Exposure Science and Epidemiology Division of the Environmental and Occupational Health Sciences Institute. He is Director of the Doctoral Degree Program in Exposure Science offered by Rutgers University. Dr. Weisel's research focuses on understanding exposure to chemical agents, with an emphasis on multi-route exposures to environmental contaminants, the association between exposure and adverse health effects, utilization of sensors for continuous exposure measurement, and development and application of biomarkers of exposure. He has examined the relationship among indoor, outdoor and personal exposures to air pollutants; documented the importance of inhalation and dermal exposure to contaminants; characterized exposures within the transportation sector; and examined exposure and health issues related to disinfection by-products in water. Dr. Weisel is past President (2007-2008) and Treasurer (2000-2003) of the International Society of Exposure Science (ISES).
Panel Experience: Dr Weisel has served on numerous international and national advisory committees, workshops and advisory review panels. His panel experience has included the National Academy of Sciences Committee to Review the U.S. EPA's “Science to Achieve Results” Research Grants (2015). Dr. Weisel served as Chair of the U.S. EPA’s “Guidelines for Human Exposure Assessment” review panel (2015) and has recently completed a term with the National Institute of Environmental Health Sciences (NIEHS) Powering Research through Innovative Methods for Mixtures in Epidemiology (PRIME) R01 Study Section (2016). Dr. Weisel is currently a member of the EPA Chemical Safety for Sustainability Board of Scientific Counselors (BOSC) Subcommittee and is a member of the Federal Insecticide, Fungicide, and Rodenticide Act Scientific Advisory Panel (2018-2021).
- Raymond S.H. Yang, Ph.D.
Colorado State University
Affiliation: Professor (Emeritus), College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, Colorado
Expertise: Physiologically-based pharmacokinetic modeling; biologically-based computer modeling; in vitro – in vivo extrapolation; Toxicology and Risk Assessment of Chemical Mixtures and Multiple Stressors, Carcinogenesis, Reproductive and Developmental Toxicology, Neurotoxicity
Education: Ph.D., Toxicology/Entomology, North Carolina State University; B.S., Biology, National Taiwan University
Experience Summary: Dr. Raymond Yang is Professor Emeritus of Toxicology and Cancer Biology at the College of Veterinary Medicine and Biomedical Sciences, Colorado State University (CSU). Currently, Dr. Yang works part-time as an International Consultant. Part of his services includes the teaching of a “PBPK Modeling Workshop for Beginners” at CSU and elsewhere in the US, Europe, and Asia. Dr. Yang’s research interests focus on physiologically-based pharmacokinetic/ pharmacodynamic (PBPK/PD) modeling, and other biologically-based computer modeling with a special emphasis on the toxicology and risk or safety assessment of chemical mixtures, poly-pharmacy, and multiple stressors, including radiation. Dr. Yang has had extensive research and administrative experience in academia, chemical industry, and the federal government and is a Fellow of the Academy of Toxicological Sciences.
Panel Experience: Dr. Yang has served on many prestigious national and international scientific committees and advisory panels as a member of the Safe Drinking Water Subcommittee on Mixtures, National Research Council/National Academy of Sciences (NAS) (1987-1988); Air Quality Science Advisory Board member, State of Colorado (1992-1998); Steering Committee Member, Decision Support Methodologies for Human Risk Assessment of Toxic Substances, Agency for Toxic Substance and Disease Registry (ATSDR), Department of Health and Human Services (DHHS) (1994-1999); member on the Committee on Interactions of Drugs, Biologics, and Chemicals in Deployed U. S. Military Forces, Institute of Medicine (IOM), NAS (1995-1996); Expert Panel Member, Risk Assessment for Mixtures of Drinking Water Disinfection-Byproducts, International Life Sciences Institute/U.S.EPA, Washington, DC (1996-1997); Commissioned author on Health Risks and Preventive Research Strategy for Deployed U.S. Forces from Toxicologic Interactions Among Potentially Harmful Agents, National Research Council, NAS (1998-1999); Expert Panel member for Chemical Mixtures, Health Council of the Netherlands (2000); member of the Society of Toxicology Expert Panel on Chemical mixtures (2001-2002); Chemical Mixture Committee member to National Occupational Research Agenda, National Institute for Occupational Safety and Health (NIOSH) (2001-2010); member of the Environmental Health Sciences Review Committee (Study Section for Center Grants, and Training Grants), National Institute of Environmental Health Sciences (NIEHS), National Institutes of Health (NIH), DHHS (2001-2005); Board of Scientific Counselors, Agency for Toxic Substances and Disease Registry (ATSDR) and National Center for Environmental Health (NCEH), CDC, DHHS (2004-2007); International Workshop Panel Member on Mixture Toxicity, Society of Environmental Toxicology and Chemistry (SETAC)/NoMiracle (European Union) (2006); Various capacities as a Scientific Advisory Member, National Health Research Institutes, Zhunan, Taiwan (2008-present). Dr. Yang was appointed as an ad hoc participant for the Federal Insecticide, Fungicide, and Rodenticide Act Scientific Advisory Panel reviewing PBPK Modeling Applications in Risk Assessments of Six Pesticides (2017). Dr. Yang is currently a member of the FIFRA SAP (2018-2021).