An official website of the United States government.

Analog Identification Methodology (AIM) Tool

The Analog Identification Methodology (AIM) is a downloadable software program that facilitates analog analysis and data identification in support of chemical assessment or read-across approaches to help scientists and chemical managers predict potential hazards of untested chemicals.

Key characteristics of the program include:

  • Ability to conduct comprehensive structural analysis of chemicals using over 700 individual atoms, groups and super fragments indexed in a predefined database
  • Uses structural analysis to match potential analogs from an inventory of over 86,000 chemicals with publicly available measured data and links to the data sources
  • Ability to recode defined substitutions or exclusion rules for the refinement of analog search strategies

AIM software is available for free and is posted below as a downloadable software program without licensing requirements. Information on use and set-up is provided in the AIM User's Manual.

Analog Identification Methodology (AIM) Download(1 pg, 104 MB)

Disclaimer: Experimental data sources identified by AIM are not endorsed by EPA; nor does EPA vouch for the quality or accuracy of the data. Furthermore, professional judgement is needed to determine adequacy of analogs identified by AIM.

EPA Technical Contact:

Cathy Fehrenbacher, U.S. EPA
Office of Chemical Safety and Pollution Prevention
Risk Assessment Division
1200 Pennsylvania Ave., N.W.
Washington, DC 20460-0001
Phone: 202-564-8551
email: fehrenbacher.cathy@epa.gov

Tracy Wright, U.S. EPA
Office of Chemical Safety and Pollution Prevention
Risk Assessment Division
1200 Pennsylvania Ave., N.W.
Washington, DC 20460-0001
Phone: 202-564-9923
email: wright.tracy@epa.gov