Analog Identification Methodology (AIM) Tool

The Analog Identification Methodology (AIM) is a downloadable software program that facilitates analog analysis and data identification in support of chemical assessment or read-across approaches to help scientists and chemical managers predict potential hazards of untested chemicals.

Key characteristics of the program include:

• Ability to conduct comprehensive structural analysis of chemicals using over 700 individual atoms, groups and super fragments indexed in a predefined database
• Uses structural analysis to match potential analogs from an inventory of over 86,000 chemicals with publicly available measured data and links to the data sources
• Ability to recode defined substitutions or exclusion rules for the refinement of analog search strategies

AIM software is available for free and is posted below as a downloadable software program without licensing requirements. Information on use and set-up is provided in the AIM User's Manual.

Analog Identification Methodology (AIM) Download (exe) (99.35 MB)

Disclaimer: Experimental data sources identified by AIM are not endorsed by EPA; nor does EPA vouch for the quality or accuracy of the data. Furthermore, professional judgement is needed to determine adequacy of analogs identified by AIM. Note that the AIM software has not been supported or updated since 2012.

EPA Technical Contact:

Chris Janson
Office of Pollution Prevention and Toxics 
New Chemicals Division
1201 Pennsylvania Ave, NW 
Washington, DC 20460 
e-mail: janson.chris@epa.gov