Laws & Regulations

PRIA FY2018: Process Improvements in the Pesticide Program

20168 PRIA Annual Report documents

PRIA FY2018: Documents on Maintenance Fees

pria annual report 2018 documents

Implementing the Pesticide Registration Improvement Act - Fiscal Year 2014

pria fees Annual Report 2014

Appendix A: FY 2014

pria fees

Guidance on Cumulative Risk Assessment of Pesticide Chemicals that have a Common Mechanism of Toxicity

This document provides guidance to OPP scientists for evaluating and estimating the potential human risks associated with such multichemical and multipathway exposures to pesticides. This process is referred to as cumulative risk assessment.

Consideration of the FQPA Safety Factor and Other Uncertainty Factors in Cumulative Risk Assessment of Chemicals Sharing a Common Mechanism of Toxicity

This guidance document provides OPP's current thinking on application of the provision in FFDCA about an additional safety factor for the protection of infants and children in the context of cumulative risk assessments.

The Use of Data on Cholinesterase Inhibition for Risk Assessments of Organophosphorous and Carbamate Pesticides

This revised science policy emphasizes the weighing of all relevant evidence when selecting endpoints for the hazard assessment of anticholinesterase pesticides.

Guidance for Considering and Using Open Literature Toxicity Studies to Support Human Health Risk Assessment

This guidance was developed to assist OPP scientists and is intended for use in OPP’s risk assessments. It is intended to ensure consistent consideration, use, and documentation of information in the open literature by OPP scientists and risk assessors.

Guidance for Identifying Pesticide Chemicals and Other Substances that have a Common Mechanism Toxicity

Determination of the Appropriate FQPA Safety Factor(s) in Assessing Pesticide Tolerances

This guidance explains how EPA addresses safety factors, including the FQPA 10X factor, in setting tolerances.

Retrospective Analysis of the Immunotoxicity Study

This document forms part of the basis for the immunotoxicity study data waiver criteria. It is related to OCSPP Test Guideline 870.7800.

Dinotefuran Petition and Response

Petition and response for Dinotefuran

Carfentrazone-ethyl Petition and Response

Petition(s) and Response(s) for Carfentrazone-ethyl

General Substantiation Questions to Support CBI Claims

General Questions and Answers Concerning Confidential Business Information (CBI) Provisions of the Toxic Substances Control Act (TSCA), as amended by the Frank R. Lautenberg Chemical Safety for the 21st Century Act

Updates to the EPA List of Alternative Test Methods to Animal Testing

Listserv announcing updates to the list of Alternative Test Methods to Animal Testing

Comment Period Extended for PV29 Revised Draft Risk Evaluation

Extension of the public comment period on the revised draft risk evaluation for C.I. Pigment Violet 29 (PV29).

EPA Issues Final Guidance to Clarify PFAS Significant New Use Rule

Listserv announcing Final Guidance to Clarify PFAS Significant New Use Rule

EPA Releases Final Chemical Risk Evaluation for TCE

Listserv announcing the final RE for TCE

EPA Launches Stewardship Program to Reduce PFAS in the Marketplace

Listserv announcing PFAS LVE Stewardship Program

EPA Launches New Electronic Reporting Application for TSCA Chemical Export Notifications

Listserv announcing a new electronic reporting application for chemical export notifications under TSCA