Laws & Regulations

(Quantitative) Structure Activity Relationship [(Q)SAR] Guidance Document

Guidance Document developed by the NAFTA Technical Working Group on the Quantitative Structure Activity Relationship.

Adoption of 2022 North American Industry Classification System (NAICS) Codes for TRI Reporting

A page to explain EPA's 2022 NAICS update rule

Guidance on FIFRA 24(c) Registrations

Under the authority of §24(c) of FIFRA, states may register an additional use of a federally registered pesticide product, or a new end use product to meet special local needs. Learn about the process and how EPA reviews these registrations.

Public Notification - RTCR Failure to Correct Sanitary Defect or Failure to Conduct an Assessment Violation Template

When a PWS receives a Treatment Technique Violation following an RTCR Level 1 or Level 2 assessment, it must issue a public notice to inform consumers of that violation. This template can be used as a guide to prepare that public notice.

TSCA Biotechnology Regulatory and Policy-Related Resources

Includes final risk assessment documents for submissions under TSCA section 5.

Polymer Exemption for New Chemicals under the Toxic Substances Control Act (TSCA)

EPA has established an exemption for certain polymers to encourage manufacturers to make safer polymers. To learn more about this exemption, eligibility, and it's requirements, read this overview of the exemption.

TSCA Section 5(a)(3)(C) Determination for Premanufacture Number (PMN) P-19-0152

This document describes EPA's pre-manufacture notice review determination under amended TSCA for P-19-0152.

TSCA Section 5(a)(3)(C) Determination for Premanufacture Number (PMN) P-19-0058

This document describes EPA's pre-manufacture notice review determination under amended TSCA for P-19-0058.

TSCA Section 5(a)(3)(C) Determination for Premanufacture Number (PMN) P-19-0146

This document describes EPA's pre-manufacture notice review determination under amended TSCA for P-19-0146.

TSCA Section 5(a)(3)(C) Determination for Premanufacture Number (PMN) P-18-0330

This document describes EPA's pre-manufacture notice review determination under amended TSCA for P-18-0330.

TSCA Section 5(a)(3)(C) Determination for Premanufacture Number (PMN) P-20-0099

This document describes EPA's pre-manufacture notice review determination under amended TSCA for P-20-0099.

TSCA Section 5(a)(3)(C) Determination for Premanufacture Number (PMN) P-18-0029

This document describes EPA's pre-manufacture notice review determination under amended TSCA for P-18-0029.

TSCA Section 5(a)(3)(C) Determination for Premanufacture Number (PMN) P-18-0213

This document describes EPA's pre-manufacture notice review determination under amended TSCA for P-18-0213.

TSCA Section 5(a)(3)(C) Determination for Premanufacture Number (PMN) P-20-0111

This document describes EPA's pre-manufacture notice review determination under amended TSCA for P-20-0111.

TSCA Section 5(a)(3)(C) Determination for Premanufacture Number (PMN) P-18-0336

This document describes EPA's pre-manufacture notice review determination under amended TSCA for P-18-0336.

TSCA Section 5(a)(3)(C) Determination for Premanufacture Number (PMN) P-18-0337

This document describes EPA's pre-manufacture notice review determination under amended TSCA for P-18-0337.

TSCA Section 5(a)(3)(C) Determination for Premanufacture Number (PMN) P-19-0162

This document describes EPA's pre-manufacture notice review determination under amended TSCA for P-19-0162.

TSCA Section 5(a)(3)(C) Determination for Premanufacture Number (PMN) P-20-0066

This document describes EPA's pre-manufacture notice review determination under amended TSCA for P-20-0066.

TSCA Section 5(a)(3)(C) Determination for Premanufacture Number (PMN) P-18-0334

This document describes EPA's pre-manufacture notice review determination under amended TSCA for P-18-0334.

TSCA Section 5(a)(3)(C) Determination for Premanufacture Number (PMN) P-17-0396

This document describes EPA's pre-manufacture notice review determination under amended TSCA for P-17-0396.