EPA Registers Products with New Active Ingredient Florylpicoxamid
Released on May 29, 2025
Today, the U.S. Environmental Protection Agency (EPA) registered three products containing the new active ingredient florylpicoxamid, a broad-spectrum fungicide that can be used on food crops and golf courses. Florylpicoxamid targets several fungi that cause damage and financial loss, giving farmers an additional tool to help manage crops and grow more food for our country.
Florylpicoxamid is expected to be a useful addition to Integrated Pest Management (IPM) programs, as it can be used in rotation with other fungicides to reduce potential resistance in crops and turf. IPM provides an effective and environmentally sensitive approach to pest control by focusing on prevention and using pesticides only as needed.
The florylpicoxamid registrations are supported by human health and ecological risk assessments as well as a biological evaluation for the pesticide under the Endangered Species Act (ESA). No human health risks of concern were identified when florylpicoxamid is used according to the label. EPA has not identified any potential risks of concern for mammals, birds, terrestrial-phase amphibians, reptiles, aquatic plants or honeybees on an acute or chronic exposure basis when florylpicoxamid is used according to the label. However, EPA identified potential risks for fish, aquatic-phase amphibians, aquatic invertebrates, other terrestrial invertebrates and terrestrial and semi-aquatic plants.
The following mitigation measures found on the products’ labeling address on- and off-field effects to non-target species, including listed species:
- Instructing users to access and follow any applicable endangered species bulletin from “Bulletins Live! Two” web-based system for all additional directions and restrictions.
- Approved for use in the contiguous United States and Hawaii only.
- For golf courses, use only on tees, greens and fairways. Do not use florylpicoxamid containing products on roughs.
With these mitigations in place, EPA’s final biological evaluation predicts that the use of florylpicoxamid will not result in a likelihood of future jeopardy of any listed species, or a likelihood of adverse modification for any designated critical habitat.
EPA has initiated ESA consultation and shared its findings with the U.S. Fish and Wildlife Service and the National Marine Fisheries Service (collectively referred to as the Services). During formal consultation, the Services use the information in EPA’s final biological evaluation to inform their biological opinions. While EPA has made predictions about the potential likelihood of future jeopardy/adverse modification as part of its biological evaluation, the Services are responsible for making the actual final jeopardy/adverse modification findings. If the Services determine in their final biological opinions that additional mitigations are necessary to address any jeopardy/adverse modification determination or to address any unintentional harm known as incidental take, then EPA will work with the registrant to ensure that any necessary registration or labeling changes are made.
All the supporting documents related to florylpicoxamid are available in docket EPA-HQ-OPP-2020-0449 at www.regulations.gov.