Skip to main content
U.S. flag

An official website of the United States government

Here’s how you know

Dot gov

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

HTTPS

Secure .gov websites use HTTPS
A lock (LockA locked padlock) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

    • Environmental Topics
    • Air
    • Bed Bugs
    • Cancer
    • Chemicals, Toxics, and Pesticide
    • Emergency Response
    • Environmental Information by Location
    • Health
    • Land, Waste, and Cleanup
    • Lead
    • Mold
    • Radon
    • Research
    • Science Topics
    • Water Topics
    • A-Z Topic Index
    • Laws & Regulations
    • By Business Sector
    • By Topic
    • Compliance
    • Enforcement
    • Laws and Executive Orders
    • Regulations
    • Report a Violation
    • Environmental Violations
    • Fraud, Waste or Abuse
    • About EPA
    • Our Mission and What We Do
    • Headquarters Offices
    • Regional Offices
    • Labs and Research Centers
    • Planning, Budget, and Results
    • Organization Chart
    • EPA History

Breadcrumb

  1. Home
  2. Pesticides

EPA Seeks Comment on Proposal to Harmonize Human Subjects Research Regulations with Revised Common Rule

For Release: December 6, 2018

On December 6, 2018, EPA published in the Federal Register a Notice of Proposed Rulemaking for public comment. The proposed rule seeks to harmonize EPA-specific human subjects research regulations with the revised Common Rule that goes into effect on January 21, 2019. EPA and other participating federal agencies follow the Common Rule on the ethical protection of human subjects participating in research projects.

The revisions to the Common Rule create a discrepancy within some EPA-specific regulations. EPA added those regulations in 2006 in response to a congressional mandate to provide additional protection to vulnerable populations by prohibiting intentional exposure studies on children and pregnant or breast-feeding women. The regulations apply to research conducted or sponsored by EPA or submitted to EPA for regulatory purposes.

The proposed rulemaking harmonizes EPA-specific regulations with revisions to the Common Rule to resolve those discrepancies; it does not change EPA’s protection of human subjects.Comments must be submitted to Docket # EPA–HQ–ORD–2018–0280 at www.regulations.gov on or before February 4, 2019.

Pesticides

  • A-Z Index
  • Antimicrobial Pesticides
  • Biopesticides
Contact Us About Pesticides
Contact Us to ask a question, provide feedback, or report a problem.
Last updated on March 6, 2025
  • Assistance
  • Spanish
  • Arabic
  • Chinese (simplified)
  • Chinese (traditional)
  • French
  • Haitian Creole
  • Korean
  • Portuguese
  • Russian
  • Tagalog
  • Vietnamese
United States Environmental Protection Agency

Discover.

  • Accessibility Statement
  • Budget & Performance
  • Contracting
  • EPA www Web Snapshot
  • Grants
  • No FEAR Act Data
  • Plain Writing
  • Privacy
  • Privacy and Security Notice

Connect.

  • Data
  • Inspector General
  • Jobs
  • Newsroom
  • Regulations.gov
  • Subscribe
  • USA.gov
  • White House

Ask.

  • Contact EPA
  • EPA Disclaimers
  • Hotlines
  • FOIA Requests
  • Frequent Questions
  • Site Feedback

Follow.