Skip to main content
U.S. flag

An official website of the United States government

Here’s how you know

Dot gov

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

HTTPS

Secure .gov websites use HTTPS
A lock (LockA locked padlock) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

    • Environmental Topics
    • Air
    • Bed Bugs
    • Cancer
    • Chemicals, Toxics, and Pesticide
    • Emergency Response
    • Environmental Information by Location
    • Health
    • Land, Waste, and Cleanup
    • Lead
    • Mold
    • Radon
    • Research
    • Science Topics
    • Water Topics
    • A-Z Topic Index
    • Laws & Regulations
    • By Business Sector
    • By Topic
    • Compliance
    • Enforcement
    • Laws and Executive Orders
    • Regulations
    • Report a Violation
    • Environmental Violations
    • Fraud, Waste or Abuse
    • About EPA
    • Our Mission and What We Do
    • Headquarters Offices
    • Regional Offices
    • Labs and Research Centers
    • Planning, Budget, and Results
    • Organization Chart
    • EPA History

Regulation of Biotechnology under TSCA and FIFRA

  • Now Available: New Tool for Biotechnology Regulation

    Check out the latest joint effort from USDA, EPA, and FDA to help biotechnology product developers understand the regulatory requirements and approval process across agencies.

Learn About Biotechnology and Emerging Technology

  • Overview of Plant-Incorporated Protectants
  • Overview of Emerging Mosquito Control Technologies
  • Overview of GMO Foods and the Feed Your Mind Initiative

Managing Biotechnology Pest Resistance

  • Insect Resistance Management for Bt Plant-Incorporated Protectants
  • Framework to Delay Corn Rootworm Resistance

Overview of Biotechnology and Emerging Technology Regulation

  • Modernizing the Regulatory System for Biotechnology Products
  • Regulation of Genetically Engineered Microorganisms under FIFRA, FFDCA, and TSCA

Biotechnology Under TSCA

  • Overview of Biotechnology Under TSCA
  • TSCA Biotechnology Regulations
  • Filing a Biotechnology Submission Under TSCA
  • Status of TSCA Biotechnology Cases Reviewed Before June 22, 2016
  • Status of TSCA Biotechnology Cases Reviewed After June 22, 2016

Biotechnology Under FIFRA

  • Introduction to Biotechnology Regulation for Pesticides
  • Regulation of Biotechnology for Pest Management
  • Biopesticide Science Advisory (SAP) Meetings

Webinars and Seminars

  • Biotechnology Webinars
  • Biotechnology Seminars

News and Events

  •  EPA, FDA, and USDA issued a stakeholder comments report on the Coordinated Framework for the Regulation of Biotechnology.
    Read report.
  • Plain-language information on agency roles, responsibilities and processes for the regulation of products of biotechnology are now available.
    View document.
  • The Plan for Regulatory Reform under the Coordinated Framework for the Regulation of Biotechnology is now available.
    View document.
  • In March 2022, EPA expanded and extended testing of genetically engineered mosquitoes to reduce mosquito populations.
    Read EPA’s statement.

Related Information

  • Overview of Biopesticides
  • Unified EPA, FDA, USDA Website for Biotechnology Regulation
  • Pesticide Registration
  • Assessing and Managing Chemicals Under TSCA
  • Find More Pesticide Information

Other Resources

  • U.S. Food and Drug Administration: Agricultural Biotechnology and the Feed Your Mind Initiative
  • Organization for Economic Co-operation and Development: Conference on RNAi Based Pesticides
  • Frontiers in Plant Science: Considerations and Regulatory Approaches in the USA and in the EU for dsRNA-Based Externally Applied Pesticides for Plant Protection
Contact Us to ask a question, provide feedback, or report a problem.
Last updated on May 1, 2025
  • Assistance
  • Spanish
  • Arabic
  • Chinese (simplified)
  • Chinese (traditional)
  • French
  • Haitian Creole
  • Korean
  • Portuguese
  • Russian
  • Tagalog
  • Vietnamese
United States Environmental Protection Agency

Discover.

  • Accessibility Statement
  • Budget & Performance
  • Contracting
  • EPA www Web Snapshot
  • Grants
  • No FEAR Act Data
  • Plain Writing
  • Privacy
  • Privacy and Security Notice

Connect.

  • Data
  • Inspector General
  • Jobs
  • Newsroom
  • Regulations.gov
  • Subscribe
  • USA.gov
  • White House

Ask.

  • Contact EPA
  • EPA Disclaimers
  • Hotlines
  • FOIA Requests
  • Frequent Questions
  • Site Feedback

Follow.