Laws & Regulations

Commence Construction

Explanation of the meaning of Commence Construction

Begin Actual Construction

Explanation of the meaning of Begin Actual Construction

Fact Sheet: Benzidine-Based Chemical Substances

EPA's existing chemicals programs address pollution prevention, risk assessment, hazard and exposure assessment and/or characterization, and risk management for chemicals substances in commercial use.

Guidance for Considering and Using Open Literature Toxicity Studies to Support Human Health Risk Assessment

This guidance was developed to assist OPP scientists and is intended for use in OPP’s risk assessments. It is intended to ensure consistent consideration, use, and documentation of information in the open literature by OPP scientists and risk assessors.

The Use of Data on Cholinesterase Inhibition for Risk Assessments of Organophosphorous and Carbamate Pesticides

This revised science policy emphasizes the weighing of all relevant evidence when selecting endpoints for the hazard assessment of anticholinesterase pesticides.

Consideration of the FQPA Safety Factor and Other Uncertainty Factors in Cumulative Risk Assessment of Chemicals Sharing a Common Mechanism of Toxicity

This guidance document provides OPP's current thinking on application of the provision in FFDCA about an additional safety factor for the protection of infants and children in the context of cumulative risk assessments.

Guidance on Cumulative Risk Assessment of Pesticide Chemicals that have a Common Mechanism of Toxicity

This document provides guidance to OPP scientists for evaluating and estimating the potential human risks associated with such multichemical and multipathway exposures to pesticides. This process is referred to as cumulative risk assessment.

Industrial Sectors Subject to Chemical Data Reporting

A table of CDR-covered Industrial Sectors

Manufacturer-Requested Risk Evaluation of Diisononyl Phthalate (DINP)

Manufacturer-requested risk evaluation

eCDRweb Webinar, May 2012

eCDRweb highlights and an overview of DX Registration and CDR Web Tool.

CDR Registration in CDX

This document is an overview presentation of the CDX Registration Process.

Instructions for the 2012 TSCA Chemical Data Reporting

This document, which pertains to EPA CDR reporting during 2012, updates guidance issued for reporting in 2006 to incorporate instructions relevant to 2012 reporting. It provides detailed information and examples to in reporting under the CDR rule.

Chemicals Reported for the 2012 Chemical Data Reporting (CDR) by CASRN or Accession Number

During the 2012 reporting cycle, Chemical Data Reporting (CDR) information was provided by manufacturers (including importers) for 7,674 individual chemicals.

Public Webinar on Proposed TSCA Data Reporting Rule

This page has info on the TSCA data reporting rule webinar that took place july 27 2021

General Substantiation Questions to Support CBI Claims

General Questions and Answers Concerning Confidential Business Information (CBI) Provisions of the Toxic Substances Control Act (TSCA), as amended by the Frank R. Lautenberg Chemical Safety for the 21st Century Act

Carfentrazone-ethyl Petition and Response

Petition(s) and Response(s) for Carfentrazone-ethyl

Dinotefuran Petition and Response

Petition and response for Dinotefuran

Retrospective Analysis of the Immunotoxicity Study

This document forms part of the basis for the immunotoxicity study data waiver criteria. It is related to OCSPP Test Guideline 870.7800.

Guidance for Identifying Pesticide Chemicals and Other Substances that have a Common Mechanism Toxicity

Implementing the Pesticide Registration Improvement Extension Act - Fiscal Year 2018

pria fees Annual Report 2018