The formats and instructions in these documents are designed to be used as an example or guide for registrants to format electronic files for submission of animal toxicology data to the EPA's Office of Pesticide Programs for review in support of registration and reevaluation of pesticides. They are based upon, and are intended to be consistent with, similar guidance published by the Food and Drug Administration (FDA). 

• Chronic subchronic toxicity studies (PDF)(20 pp, 355 K)
• Developmental neurotoxicity studies (PDF)(34 pp, 581 K)
• Prenatal developmental toxicity studies (PDF)(18 pp, 337 K)
• Multi-generation reproduction studies (PDF)(32 pp, 481 K)