Pesticide Registration Manual

The Pesticide Registration Manual is a resource for companies and individuals who want to have their pesticide products registered for sale in the United States. The manual describes the EPA's review and decision-making process for registering a pesticide product and its use. Detailed information for pesticide registrants (the company or individual applying to register a pesticide) concerning their responsibilities before, during and after the review process is also included in the manual.

Title	PDF
Introduction	Registration Manual: Introduction (pdf) (186.6 KB)
How to Register a Pesticide Product – A Guide for Applicants New to the Process	Registration Manual: How to Register a Pesticide (pdf) (304.61 KB)
Chapter 1: Requirements for Pesticide Registration and Registrant Obligations	Registration Manual: Chapter 1 (pdf) (337.72 KB)
Chapter 2: Registering a Pesticide Product	Registration Manual: Chapter 2 (pdf) (447.9 KB)
Chapter 3: Additional Considerations for Biopesticide Products	Registration Manual: Chapter 3 (pdf) (413.29 KB)
Chapter 4: Additional Considerations for Antimicrobial Products	Registration Manual: Chapter 4 (pdf) (411.29 KB)
Chapter 5: Registration Fees	Registration Manual: Chapter 5 (pdf) (291.84 KB)
Chapter 6: Amending a Registered Pesticide Product	Registration Manual: Chapter 6 (pdf) (267.71 KB)
Chapter 7: Notifications and Minor Formulation Amendments	Registration Manual: Chapter 7 (pdf) (307.08 KB)
Chapter 8: Inert Ingredients	Registration Manual: Chapter 8 (pdf) (213.9 KB)
Chapter 9: Supplemental Distribution of a Registered Pesticide	Registration Manual: Chapter 9 (pdf) (199.93 KB)
Chapter 10: Data Compensation Requirements	Registration Manual: Chapter 10 (pdf) (397.93 KB)
Chapter 11: Tolerance Petitions	Registration Manual: Chapter 11 (pdf) (280.79 KB)
Chapter 12: Applying for an Experimental Use Permit	Registration Manual: Chapter 12 (pdf) (268.11 KB)
Chapter 13: Devices	Registration Manual: Chapter 13 (pdf) (305.49 KB)
Chapter 14: How to Obtain an EPA Company or Establishment Number and Change of Address of Contact Information	Registration Manual: Chapter 14 (pdf) (240.49 KB)
Chapter 15: Submitting Data and Confidential Business Information	Registration Manual: Chapter 15 (pdf) (232.24 KB)
Chapter 16: Transfer of Product Registrations and Data Rights	Registration Manual: Chapter 16 (pdf) (264.02 KB)
Chapter 17: State Regulatory Authority	Registration Manual: Chapter 17 (pdf) (236.98 KB)
Chapter 18: Other Federal or State Agency Requirements	Registration Manual: Chapter 18 (pdf) (305.27 KB)
Chapter 19: How to Obtain Publications	Registration Manual: Chapter 19 (pdf) (205.22 KB)
Chapter 20: Forms and How to Obtain Them	Registration Manual: Chapter 20 (pdf) (226.93 KB)
Chapter 21: Directions for Submitting Applications and Contacting EPA	Registration Manual: Chapter 21 (pdf) (318.05 KB)
Appendix A: Guidance Documents	Registration Manual: Appendix A (pdf) (129.13 KB)
Appendix B: Examples of Registrant Documents	Registration Manual: Appendix B (pdf) (132.98 KB)
Appendix C: Pesticide Forms Overview Table	Registration Manual: Appendix C (pdf) (161.09 KB)
Appendix D: Examples of Completed Forms	Registration Manual: Appendix D (pdf) (140.38 KB)

EPA Contacts for Support

Conventional Chemicals
OPP RD Ombudsman
(opp_rd_ombudsman@epa.gov)
PRIA Ombudsman
Seiichi Murasaki
(murasaki.seiichi@epa.gov)
Antimicrobial Chemicals
pesticidequestions@epa.gov
Biopesticide Chemicals
BPPDQuestions
(bppdquestions@epa.gov)

Helpful Resources

Comments or technical issues about the Registration Manual? Email us.