Skip to main content
U.S. flag

An official website of the United States government

Here’s how you know

Dot gov

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

HTTPS

Secure .gov websites use HTTPS
A lock (LockA locked padlock) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

    • Environmental Topics
    • Air
    • Bed Bugs
    • Cancer
    • Chemicals, Toxics, and Pesticide
    • Emergency Response
    • Environmental Information by Location
    • Health
    • Land, Waste, and Cleanup
    • Lead
    • Mold
    • Radon
    • Research
    • Science Topics
    • Water Topics
    • A-Z Topic Index
    • Laws & Regulations
    • By Business Sector
    • By Topic
    • Compliance
    • Enforcement
    • Laws and Executive Orders
    • Regulations
    • Report a Violation
    • Environmental Violations
    • Fraud, Waste or Abuse
    • About EPA
    • Our Mission and What We Do
    • Headquarters Offices
    • Regional Offices
    • Labs and Research Centers
    • Planning, Budget, and Results
    • Organization Chart
    • EPA History

Breadcrumb

  1. Home
  2. Ozone Layer Protection
  3. Background and Science

Atmospheric and Health Effects Framework Model Estimating Ultraviolet Radiation-induced Health Effects

The Atmospheric and Health Effects Framework (AHEF) model is used by the EPA to evaluate human health effects associated with a depleted stratospheric ozone layer. It estimates the number of skin cancer and cataract cases and deaths from skin cancer in the United States that will be prevented by protecting the ozone layer, which results in a decrease of the ultraviolet (UV) radiation reaching Earth’s surface that causes these diseases. The AHEF combines satellite ozone measurements with projected emissions of ozone-depleting substances (ODS) and demographic data to estimate the probable difference in deaths and skin cancer/cataract incidences by comparing different ODS emissions scenarios. Example scenarios include: no Montreal Protocol on Substances that Deplete the Ozone Layer (Montreal Protocol); the original 1987 Montreal Protocol; and the Montreal Protocol as amended and adjusted.

The May 2020 report estimates that full implementation of the Montreal Protocol on Substances that Deplete the Ozone Layer is expected to prevent approximately 443 million cases of skin cancer, 2.3 million skin cancer deaths, and 63 million cases of cataracts for people in the United States born in the years 1890–2100.

AHEF Infographic

The AHEF estimates the incidences of cutaneous malignant melanoma (melanoma) and keratinocyte skin cancer. Melanoma is a potentially life-threatening disease and is the most serious type of skin cancer. It occurs most frequently in persons over age 40 with light complexion and hair color. Keratinocyte cancer, or “non-melanoma skin cancer,” includes squamous cell carcinoma, basal cell carcinoma, and several other rare types. The AHEF also models incidences of cataract, which is a clouding of the eye’s naturally clear lens that can block vision and cause blindness. While cataract related to age can have a number of potential causes, lifelong exposure to UV radiation can play a big role.

The AHEF model is continually being updated to use the most recent data on ODS emissions, ozone depletion, UV exposure, demographics, and human health effects. From new scientific findings to updated population data, the AHEF model has been regularly revised since it was created to present the most up-to-date information. The 2020 version incorporates changes to various atmospheric and chemical parameters, updated population data, changes to methodologies, and modernization and streamlining of the underlying computer code.

Previous AHEF reports are also available below.

  • 2020 Report: Atmospheric and Health Effects Framework Model (pdf) (1.38 MB)
  • 2015 Report: Atmospheric and Health Effects Framework Model (pdf) (995.5 KB)
  • 2010 Report: Protecting the Ozone Layer Protects Eyesight (pdf) (1.53 MB)
  • AHEF Questions and Answers (pdf) (98.45 KB)

Ozone Layer Protection

  • Background and Science
    • Basic Ozone Layer Science
    • Health and Environmental Effects of Ozone Layer Depletion
    • Ozone-Depleting Substances
    • Current State of the Ozone Layer
    • Atmospheric and Health Effects Framework Model
    • EPA’s Vintaging Model of ODS Substitutes
  • Regulatory Programs Under the Clean Air Act
    • Ozone Protection under Title VI of the Clean Air Act
    • ODS Phaseout Program
    • Nonessential Products Ban
    • Significant New Alternatives Policy (SNAP) Program
    • Stationary Refrigeration and Air Conditioning Program
    • Motor Vehicle Air Conditioning Program
    • Enforcement Actions Under Title VI of the Clean Air Act
  • Related Actions and Programs
  • International Action
Contact Us For Information About Ozone Layer Science
Contact Us to ask a question, provide feedback, or report a problem.
Last updated on April 7, 2025
  • Assistance
  • Spanish
  • Arabic
  • Chinese (simplified)
  • Chinese (traditional)
  • French
  • Haitian Creole
  • Korean
  • Portuguese
  • Russian
  • Tagalog
  • Vietnamese
United States Environmental Protection Agency

Discover.

  • Accessibility Statement
  • Budget & Performance
  • Contracting
  • EPA www Web Snapshot
  • Grants
  • No FEAR Act Data
  • Plain Writing
  • Privacy
  • Privacy and Security Notice

Connect.

  • Data
  • Inspector General
  • Jobs
  • Newsroom
  • Regulations.gov
  • Subscribe
  • USA.gov
  • White House

Ask.

  • Contact EPA
  • EPA Disclaimers
  • Hotlines
  • FOIA Requests
  • Frequent Questions
  • Site Feedback

Follow.