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Risk Assessment

Guidelines for Mutagenicity Risk Assessment

The Guidelines for Mutagenicity Risk Assessment (hereafter Guidelines) are intended to guide Agency analysis of mutagenicity data in line with the policies and procedures established in the statutes administered by EPA. These Guidelines were developed as part of an interoffice guidelines development program under the auspices of the Office of Health and Environmental Assessment (OHEA) in the Agency s Office of Research and Development. They reflect Agency consideration of public and Science Advisory Board (SAB) comments on the Proposed Guidelines for Mutagenicity Risk Assessment published November 23, 1984 (49 FR 46314). 
This publication completes the first round of risk assessment guidelines development. These Guidelines will be revised, and new guidelines will be developed, as appropriate.
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