Risk Evaluation for 1,4-Dioxane
1,4-dioxane is a solvent used in a variety of industrial and commercial applications, such as in the manufacture of other chemicals, as a processing aid, a laboratory chemical, and in adhesives and sealants. No consumer uses for 1,4-dioxane were reported in the United States in the 2016 Chemical Data Reporting, and EPA has not identified any information indicating consumer uses. However, it may be present as an unintended contaminant at residual concentrations in commercial and consumer products that contain ethoxylated surfactants.
On this page:
- Problem Formulation for 1,4-dioxane risk evaluation under amended TSCA
- Scope of 1,4-dioxane risk evaluation under amended TSCA
- Review of 1,4-dioxane prior to the Lautenberg Act
Problem Formulation for 1,4-Dioxane Risk Evaluation under Amended TSCA
- CASRN: 123-91-1
- Initiated: December 19, 2016
- Docket: EPA-HQ-OPPT-2016-0723
This problem formulation refines the scope of the 1,4-dioxane risk evaluation by clarifying the chemical uses that EPA expects to evaluate and describing how EPA expects to conduct the evaluation. This is an important interim step prior to completing and publishing the final risk evaluation. The problem formulation document will be available for comment until August 16, 2018 in the docket listed above.
Scope of 1,4-Dioxane Risk Evaluation Under Amended TSCA
This scope document includes the hazards, exposures, conditions of use, and the potentially exposed or susceptible subpopulations the EPA expects to consider in its risk evaluation of 1,4-dioxane conducted pursuant to TSCA Section 6(b)(4).
- Read the scope document for 1,4-dioxane under amended TSCA
- View the supplemental files for the 1,4-dioxane scope document:
After releasing the scope documents, the dockets for each of the first 10 chemicals were open for public comments. Read EPA’s Responses to Public Comments Received on the Scope Documents for the First Ten Chemicals for Risk Evaluation under TSCA. This document addresses cross-cutting public comments received in response to EPA publishing the scope documents.
Review of 1,4-Dioxane Prior to the Lautenberg Act
Prior to the Lautenberg Act, EPA began the review of 1,4-dioxane and published the following information.