Risk Evaluation for 1,4-Dioxane
1,4-dioxane is a solvent used in a variety of industrial and commercial applications, such as in the manufacture of other chemicals, as a processing aid, a laboratory chemical, and in adhesives and sealants. No consumer uses for 1,4-dioxane were reported in the United States in the 2016 Chemical Data Reporting, and EPA has not identified any information indicating consumer uses. However, it may be present as an unintended contaminant at residual concentrations in commercial and consumer products that contain ethoxylated surfactants.
On this page:
- Scope of 1,4-dioxane risk evaluation under amended TSCA
- Review of 1,4-dioxane prior to the Lautenberg Act
Scope of 1,4-Dioxane Risk Evaluation Under Amended TSCA
- CASRN: 123-91-1
- Initiated: December 19, 2016
- Docket: EPA-HQ-OPPT-2016-0723
This scope document includes the hazards, exposures, conditions of use, and the potentially exposed or susceptible subpopulations the EPA expects to consider in its risk evaluation of 1,4-dioxane conducted pursuant to TSCA Section 6(b)(4). EPA will publish and take public comment on a Problem Formulation document for 1,4-dioxane which will refine the current scope, as an additional interim step, prior to publication the draft risk evaluation. This problem formulation is expected to be released within approximately six months of publication of the scope documents.
- Read the scope document for 1,4-dioxane under amended TSCA
- View the supplemental files for the 1,4-dioxane scope document:
Review of 1,4-Dioxane Prior to the Lautenberg Act
Prior to the Lautenberg Act, EPA began the review of 1,4-dioxane and published the following information.