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Safer Chemicals Research

EPA's Safer Chemicals Research is transforming chemical risk-based decisions by conducting high-quality, innovative scientific research. The results of this research support the Agency, states, tribes, and other stakeholders in fulfilling their shared objectives to protect human health and the environment. The pressing environmental and health challenge in chemical safety evaluations has been, and continues to be, a lack of sufficient information on most chemicals used in commerce, industry, and agriculture.  

Research Areas

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  • Chemical Evaluation: Evaluating Chemicals for Health Effects
  • Complex Systems Science: Understanding Chemical In-teraction with Biological Systems
  • Knowledge Delivery & Solutions-Driven Translation to Support Decision Making: Delivering Research to Users
  • Children's Environmental Health
  • Chemicals We're Researching

Tools Hub

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  • EPA Science Models and Research Tools (SMaRT) Search
  • CompTox Chemicals Portal
  • CompTox Chemicals Dashboard Primer Videos
  • Downloadable Data

Funding & Collaborations

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  • Research Funding Opportunities
  • Small Business Innovation Research Program 
  • EPA Active Contracts Listing 
  • Collaborative Agreements for Computational Toxicology and Exposure Research 
  • Grantee Research Project Results 
  • Fellowships, Scholarships and Post-Doctoral Opportunities

Outreach & Training

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  • Outreach and Engagement Opportunities
  • New Approach Methods Training Catalogue 
  • Fact Sheets

Key Links

  • EPA Research
  • Publications, Presentations, and Other Research Products
  • About the Office of Research and Development
  • About the Center for Computational Toxicology and Exposure

  • Chemical Substances and Toxics
  • Chemical Safety for Sustainability Strategic Research Action Plan 2023-2026
  • Efforts to Reduce Animal Testing at EPA

  • Pesticides
  • Pest Control and Pesticide Safety for Consumers

Recent Research Updates

  • Science Matters Newsletter
  • Follow @EPAresearch on Twitter

Meet EPA Researchers

  • Dr. Jon Sobus
  • Dr. Carlie LaLone
  • Dr. Kim Rogers
  • Chemical Safety Researchers at Work
Contact Us to ask a question, provide feedback, or report a problem.
Last updated on January 30, 2023
United States Environmental Protection Agency

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