EPA New Approach Methods: Efforts to Reduce Use of Vertebrate Animals in Chemical Testing
EPA is prioritizing ongoing efforts to develop and use New Approach Methods (NAMs) to test chemicals for health effects. Using NAMs will help reduce the use of Vertebrate Animals in chemical testing while ensuring protection of human health and the environment.
The definition of NAMs has evolved over time. Currently, it is broadly descriptive reference to any non Vertebrate Animals technology, methodology, approach, or combination thereof that can be used to provide information on chemical hazard and risk assessment. NAMs are functionally equivalent to “alternatives" to mammal testing.
- NAMs Work Plan for Reducing the Use of Vertebrate Animals in Chemical Testing
- Conferences on the State of the Science on Development and Use of NAMs for Chemical Safety Testing
- List of NAMs per Section 4(h)(2)(C) of TSCA
- [NEW] Summary Report: U.S. EPA New Approach Methods (NAMs) Conference 2022 (pdf) (662.24 KB, 4/21/2023)
- [CLOSED MARCH 3, 2023]: Nominations for the formation of two ad hoc Board of Scientific Counselors (BOSC) panels
- [CLOSED MARCH 20, 2023]: Open for Public Comment: Availability of New Approach Methodologies in the Endocrine Disruptor Screening Program
- New Chemicals Collaborative Research Program