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EPA New Approach Methods: Efforts to Reduce Use of Vertebrate Animals in Chemical Testing

researcher working on New Approach Methods

EPA is prioritizing ongoing efforts to develop and use New Approach Methods (NAMs) to test chemicals for health effects. Using NAMs will help reduce the use of Vertebrate Animals in chemical testing while ensuring protection of human health and the environment.

The definition of NAMs has evolved over time. Currently, it is broadly descriptive reference to any non Vertebrate Animals technology, methodology, approach, or combination thereof that can be used to provide information on chemical hazard and risk assessment. NAMs are functionally equivalent to “alternatives" to mammal testing.

  • NAMs Work Plan for Reducing the Use of Vertebrate Animals in Chemical Testing
  • Conferences on the State of the Science on Development and Use of NAMs for Chemical Safety Testing
  • List of NAMs per Section 4(h)(2)(C) of TSCA

Resources

  • Alternative Toxicity Testing Report to Congress
  • TSCA Alternative to Mammal Testing
  • Pesticides
  • NAMs Research
  • NAMs Training Site

News

  • [NEW]  Summary Report: U.S. EPA New Approach Methods (NAMs) Conference 2022 (pdf) (662.24 KB, 4/21/2023)
  • [CLOSED MARCH 3, 2023]: Nominations for the formation of two ad hoc Board of Scientific Counselors (BOSC) panels
    • Draft EPA Transcriptomic Assessment Product (ETAP)
    • A Value of Information (VOI) case study
  • [CLOSED MARCH 20, 2023]: Open for Public Comment: Availability of New Approach Methodologies in the Endocrine Disruptor Screening Program
  • New Chemicals Collaborative Research Program
Contact Us to ask a question, provide feedback, or report a problem.
Last updated on April 21, 2023
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