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Second Annual Conference on the State of Science on Development and Use of NAMs for Chemical Safety Testing

EPA is prioritizing ongoing efforts to develop and use New Approach Methods (NAMs) to test chemicals for health effects. Using NAMs will help reduce the use of animals in chemical testing while ensuring protection of human health and the environment.  EPA hosted the Second Annual Conference on the State of the Science on Development and Use of New Approach Methods (NAMs) for Chemical Safety Testing virtually on October 19 & 20, 2020. 

EPA will initiate the planning process for the 3rd Annual EPA NAM Conference very soon and are requesting agenda suggestions. We encourage you to review these 2nd Annual NAM conference summary materials below and submit suggestions for the 3rd Annual EPA NAM Conference by emailing NAM@epa.gov .

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Conference Background

EPA’s Office of Chemical Safety and Pollution Prevention (OCSPP) and Office of Research and Development (ORD) hosted the First Annual Conference on the State of the Science on Development and Use of New Approach Methods (NAMs) for Chemical Safety Testing on December 10, 2019. The Second Annual NAMs conference was held Oct. 19-20, 2020.

Agenda topics

  • Implementation of Animal Testing Reduction at EPA
  • State of the Science in Development of NAMs (Case Studies)
  • Addressing Current Limitations in NAMs
  • Developing Scientific Confidence in NAMs

Logistical Details

Date

The conference was held virtually October 19-20, 2020

Conference Agenda, Presentations, Recordings and Materials 

2020 Agenda
Conference Summary
Recording of Day OneExit
Recording of Day TwoExit
 

Presentation

Presenter

Affiliation

Overview of EPA NAMs Work Plan

Russell Thomas

EPA

Progress on Implementing the TSCA Alternatives Strategic Plan 

Gino Scarano

EPA

Using Chemical, Biological, and In Vivo Data for NAMs: Which data do we have, and what can we do with it?

Andreas Bender

Cambridge

Transcriptome-Based Derivation of an In Vivo POD: Current and Future Utility

Kamin Johnson

Corteva

“Fit for Purpose” for Organotypic Models in Environmental Health Protection

Ivan Rusyn

Texas A&M

Retrofitting an Estrogen Receptor Transactivation Assay with Metabolic Competence

Chad Deisenroth

EPA

In Vitro Disposition of Tox21 Chemicals: Initial Results and Next Steps

David Crizer

NTP6

An OECD Harmonized Template (OHT) to Report NAM Results in Regulatory Environments: Principles and Practical Use

Clemens Wittwehr

JRC

Case Study #1: Integration of NAM Data for Evaluating Potential Developmental Neurotoxicity

Monique Perron

EPA

Case Study #2: Integration of NAM Data in a Next Generation Risk Assessment for Cosmetic Ingredients

Andrew White

Unilever

Case Study #3: Incorporating the Threshold of Toxicological Concern into Regulatory Decisions under the Amended Toxic Substances Control Act

Todd Stedeford

EPA

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