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NIEHS/EPA Children's Centers 2015 Webinar Series: Interdisciplinary Approaches to Neurodevelopment

Title:	NIEHS/EPA Children's Centers 2015 Webinar Series co-sponsored by EPA’s Office of Children’s Health Protection
Date:	Sept. 9, 2015 1:00 p.m. - 2:30 p.m. EDT
Location:	Webinar
Purpose:	Join us for this month's webinar. The webinar features presentations and interactive discussions including recent findings and new developments in children's environmental health. Topic: Interdisciplinary Approaches to Neurodevelopment Featured Speakers: Virginia Rauh Columbia University Title: Epidemiologic Studies of the Effects of Toxic Exposures on Brain and Behavior: Neuropsychological Assessment Summary: This presentation describes epidemiologic methods for studying the impact of prenatal exposure to a common organophosphate insecticide, chlorpyrifos, on cognition and behavior in a community-based sample of inner-city minority children. Results show the emergence of a signature neuropsychological profile characterized by poor fine motor dexterity, auditory attention deficits, good impulse control and no visual memory problems. Implications for potential clinical, emotional or learning impairments are discussed. Pam Lein University of California, Davis Title: Using in vitro and in vivo models to inform studies of developmental neurotoxicity Summary: This talk will summarize the iterative use of in vitro and in vivo models to inform ongoing studies examining the effects of environmental chemicals on neuronal connectivity in the developing brain. Susan Schantz University of Illinois at Urbana-Champaign Title: Assessing Neurodevelopment in Parallel Animal and Human Studies Summary: This talk will describe the approach we are using in our Children’s Environmental Health Research Center to assess the impact of prenatal chemical exposure on neurodevelopment. Brad Peterson Children's Hospital in Los Angeles Title: MRI Studies of the Brain-Based Effects of Prenatal Exposure to Environmental Toxins Summary: This presentation will summarize findings from preliminary studies on the effects that prenatal exposure to two environmental neurotoxicants -- the insecticide chlorpyrifos and the air pollutant Polycyclic Aromatic Hydrocarbons -- have on brain structure in grade school-aged children. It will also provide discuss the consequences that the brain-based effects of these toxicants are thought to have on cognition and behavior. Jennifer Lowry Discussion Moderator Children's Mercy
Contact:	Nica Louie (louie.nica@epa.gov); 703-347-8125

Presentations:

Using in vitro and in vivo models to inform understanding of developmental neurotoxicity (PDF)(16 pp, 1 MB, 11/3/2016)

Epidemiologic Studies of the Effects of Toxic Exposures on Brain and Behavior: Neuropsychological Assessment (PDF)(19 pp, 878 K, 11/3/2016)

Assessing Neurodevelopment in Parallel Animal and Human Studies (PDF)(18 pp, 2 MB, 11/3/2016)