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National Priorities: Evaluation of Antimicrobial Resistance in Wastewater and Sewage Sludge Treatment and Its Impact on the Environment Request for Applications (RFA)

OVERVIEW INFORMATION

U.S. Environmental Protection Agency
Office of Science Advisor, Policy and Engagement
Office of Research and Development

NATIONAL PRIORITIES: EVALUATION OF ANTIMICROBIAL RESISTANCE IN WASTEWATER AND SEWAGE SLUDGE TREATMENT AND ITS IMPACT ON THE ENVIRONMENT

This is the initial announcement of this funding opportunity.

Funding Opportunity Number: EPA-G2023-ORD-F1

Assistance Listing Number: 66.511

Solicitation Opening Date: May 19, 2023
Solicitation Closing Date: August 16, 2023: 11:59:59 p.m. Eastern Time

In recent years, concern has increased about the occurrence of antibiotic resistant bacteria (ARB) and antibiotic resistant genes (ARGs) that could make it more difficult to treat certain infections in animals and people. Wastewater treatment facilities are believed to be potential receptors and sources for ARB and ARGs and can act as a bridge to the environment. This RFA seeks research that will address knowledge gaps in the occurrence, fate and transport, and persistence of antimicrobial resistant organisms and genes found in municipal wastewater effluent and biosolids. The RFA also requests research on combined sewer overflows, septic systems, and small wastewater systems. Research should provide a better understanding of the impact of ARB and ARGs on receiving waters including information on the relative contribution of ARB and ARGs from wastewater as compared to other sources such as animal agriculture, animal husbandry, hospital sources, and direct industrial sources.  Research should also support the development of frameworks and methodologies for quantifying risk related to AMR in treated wastewater discharge, water reuse, and biosolids (and biosolids products) land application and beneficial use. Research results should improve our understanding of the nature, extent, selection, and removal of ARB and ARGs found in municipal wastewater effluent and biosolids.

National Priorities: Evaluation of Antimicrobial Resistance in Wastewater and Sewage Sludge Treatment and Its Impact on the Environment Request for Applications (RFA) (pdf) (656.38 KB)

National Priorities: Evaluation of Antimicrobial Resistance in Wastewater and Sewage Sludge Treatment and its Impact on the Environment Webinar Slides (pptx) (602.31 KB)

National Priorities Evaluation of Antimicrobial Resistance Info Webinar Q&As (pdf) (250.63 KB)

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Last updated on June 6, 2025
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