TRI-Listed Chemicals

In general, chemicals covered by the Toxics Release Inventory(TRI) Program are those that cause one or more of the following:

• Cancer or other chronic human health effects
• Significant adverse acute human health effects
• Significant adverse environmental effects

The current TRI toxic chemical list contains 787 individually listed chemicals and 33 chemical categories.

TRI Chemical List Changes: 1987-2022

EPA makes changes to the TRI chemical list through EPA-initiated review and through the chemical petitions process. As a result, the TRI list of reportable toxic chemicals can vary from year to year.

TRI Chemical List Changes (pdf) (253.97 KB, 1/30/2023) : All additions to and deletions from the TRI chemical list. Indicates the first or last reporting year for those chemicals.

TRI Chemicals Classified as OSHA Carcinogens

Basis of TRI OSHA Carcinogen Designation (pdf) (226.59 KB, 1/20/2023) : Lists chemicals considered to be carcinogens under the requirements adopted from the Occupational Safety and Health Administration (OSHA) (see 40 CFR §372.38(a)) and the basis for the classifications.

Persistent Bioaccumulative Toxic (PBT) Chemicals

PBT chemicals have lower reporting thresholds than other TRI chemicals. PBTs are of particular concern because they remain in the environment for long periods of time, are not readily destroyed and build up or accumulate in body tissue.

• List of PBT Chemicals Subject to TRI Reporting
• TRI PBT-Related Rulemakings
• Dioxin and Dioxin-like Compounds Toxic Equivalency Information Final Rule

TRI Chemicals and Other EPA Regulatory Programs

• Consolidated "List of Lists": EPA prepared this document to help facilities determine, for a specific chemical, whether they may be subject to reporting requirements under Sections 302 and 313 of the Emergency Planning and Community Right-to-Know Act (EPCRA), the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA or Superfund); the Resource Conservation and Recovery Act (RCRA); and Section 112(r) of the Clean Air Act.

Toxicity of TRI Chemicals

• TRI-Chemical Hazard Information Profiles (TRI-CHIP): TRI's searchable database system contains hazard information for TRI chemicals. Among other features, users can search for toxicity information from multiple information sources and identify TRI chemicals associated with a particular critical adverse human health effect.

• Agency for Toxic Substances and Disease Registry (ATSDR) ToxFAQs: ToxFAQs is a series of printable fact sheets that answer the most frequently asked questions about exposure to hazardous substances and the effects of exposure on human health. Many of these substances are also TRI chemicals. Available in multiple languages.

• Right-to-Know Hazardous Substance Fact Sheets: The New Jersey Department of Health's library includes information on more than 1,600 hazardous substances, many of which are TRI chemicals. Available in English and Spanish.

• Toxic Chemicals Added Under 1994 Chemical Expansion: Summary hazard information on the 286 chemicals that were added to the TRI in 1994.

  • Toxicity Data By Category For TRI-Listed Chemicals (pdf) (87.87 KB)
  • Acute Toxicity Data For TRI-Listed Chemicals (pdf) (9.12 KB)
  • Chronic (Non-Cancer) Toxicity Data For TRI-Listed Chemicals (pdf) (246.83 KB)
  • Cancer Data For TRI-Listed Chemicals (pdf) (24.97 KB)
  • Environmental Toxicity Data For TRI-Listed Chemicals (pdf) (57.95 KB)