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Green Chemistry Challenge Winners

On this page:

Award winners by year with links to technology summaries and podcasts (for some).

On other pages:

  • Summaries of all winning technologies in PDF format: 1996-2016 GCC Award Recipients Booklet
  • Winning technologies indexed by technology
  • Winning technologies indexed by industry sector

Disclaimer: Mention of trade names, products, or services does not convey official EPA approval, endorsement, or recommendation.


Award Winners by Year

Select a year:

2022 Award Winners

  • For Greener Synthetic Pathways
    Merck & Co., Inc. 
    Developing a greener way to make LAGEVRIO™ (molnupiravir), an antiviral treatment for COVID-19 (summary)

  • For Greener Reaction Conditions
    Amgen
    An improved manufacturing process for LUMAKRAS™ (sotorasib), a novel drug for the treatment of certain non-small cell lung cancers (summary) 

  • For Small Business
    Provivi
    Creating Provivi FAWTM , a biological pheromone-based product that controls the fall armyworm, a destructive pest of corn (summary)

  • For Academic
    Professor Song Lin of Cornell University
    Developing a new, more efficient process using electrochemistry to create large and complicated molecules that are widely used in the pharmaceutical industry (summary)

  • For Specific Environmental Benefit—Climate Change
    University of California Davis
    A technology that reduces greenhouse gas emissions by producing chemicals for making plastic from biomass rather than petroleum (summary)

2021 Award Winners

  • For Greener Synthetic Pathways
    Merck & Co., Inc. 
    Gefapixant Citrate (summary)

  • For Greener Reaction Conditions
    Bristol Myers Squibb Company
    Five sustainable reagents (summary) 

  • For Designing Greener Chemicals
    Colonial Chemical 
    Suga®Boost surface cleaner (summary)

  • For Small Business
    XploSafe LLC 
    PhosRox, a novel sorbent (summary)

  • For Academic
    Professor Srikanth Pilla of Clemson University
    Nonisocyanate polyurethane (NIPU) foam (summary)

2020 Award Winners

  • For Greener Synthetic Pathways
    Genomatica 
    Biobased Butylene Glycol (summary)
  • For Greener Reaction Conditions
    Merck & Co. 
    A Green Solution to the ProTide Synthesis Problem: Design of a Multifunctional Catalyst That Stereoselectively Assembles ProDrugs (summary)
  • For Designing Greener Chemicals
    Johns Manville, a Berkshire Hathaway Company 
    Biobased Formaldehyde-Free Thermoset Binder Formulation (summary)
  • For Small Business
    Vestaron Corporation 
    SPEAR® Insecticide: First Member of a New Class of Biopesticides That Show Efficacy Comparable to Synthetic Insecticides (summary)
  • For Academic
    Professor Steven Skerlos of the University of Michigan and Fusion Coolant Systems 
    Pure-Cut™ (summary)

2019 Award Winners

  • For Greener Synthetic Pathways
    Merck & Co. 
    Innovating for a Greener Future: Development of a Green & Sustainable Manufacturing Process for ZerbaxaTM (summary)
  • For Greener Reaction Conditions
    WSI
    TRUpathTM (summary)
  • For Small Business
    Kalion, Inc.  
    Microbially Produced High-Purity Glucaric Acid for Diverse Uses (summary)
  • For Academic
    Professor Sanjoy Banerjee of the City University of New York
    Rechargeable Alkaline Zn-MnO2 Batteries for Grid Storage Applications (summary)

2018 Award Winners

  • The US EPA did not solicit nominations for the Green Chemistry Challenge Awards in 2018. However, the American Chemical Society, who co-sponsors the EPA Green Chemistry Challenge, solicited nominations and selected awardees separately from the EPA.  More information about the 2018 winners can be found here.  

2017 Award Winners

  • For Greener Synthetic Pathways
    Merck & Co., Inc. 
    Letermovir: A Case Study in State-of-the-Art Approaches to Sustainable Commercial Manufacturing Processes in the Pharmaceutical Industry (summary)
  • For Greener Reaction Conditions
    Amgen Inc.
    Bachem 
    Green Process for Commercial Manufacture of Etelcalcetide Enabled by Improved Technology for Solid Phase Peptide Synthesis (summary)
  • For Designing Greener Chemicals
    The Dow Chemical Company 
    Papierfabrik August Koehler SE 
    Breakthrough Sustainable Imaging Technology for Thermal Paper (summary)
  • For Small Business
    UniEnergy Technologies LLC 
    The UniSystemTM: An Advanced Vanadium Redox Flow Battery for Grid-Scale Energy Storage (summary)
  • For Academic
    Professor Eric J. Schelter of University of Pennsylvania
    Simple and Efficient Recycling of Rare Earth Elements from Consumer Materials Using Tailored Metal Complexes (summary)

2016 Award Winners

  • For Greener Synthetic Pathways
    CB&I (now McDermott)
    Albemarle 
    AlkyClean® Technology: An Inherently Safer Technology for the Production of Gasoline Alkylate (summary)
  • For Greener Reaction Conditions
    Dow AgroSciences LLC 
    Instinct® Technology - Making Nitrogen Fertilizers Work More Effectively for Farmers and the Planet (summary)
  • For Designing Greener Chemicals and Specific Environmental Benefit: Climate Change
    Newlight Technologies 
    AirCarbon: Greenhouse Gas Transformed into High-Performance Thermoplastic (summary)
  • For Small Business
    Verdezyne
    Renewable Nylon Through Commercialization of BIOLONTM DDDA (summary)
  • For Academic
    Professor Paul J. Chirik of Princeton University 
    Catalysis with Earth Abundant Transition Metals (summary)

2015 Award Winners

  • For Greener Synthetic Pathways
    LanzaTech Inc. 
    LanzaTech Gas Fermentation Process (summary and picture)
  • For Greener Reaction Conditions
    Soltex (Synthetic Oils and Lubricants of Texas)
    A Novel High Efficiency Process for the Manufacture of Highly Reactive Polyisobutylene Using a Fixed Bed Solid State Catalyst Reactor System (summary and picture)
  • For Designing Greener Chemicals
    Hybrid Coating Technologies
    Nanotech Industries
    Hybrid Non-Isocyanate Polyurethane/Green PolyurethaneTM (summary and picture)
  • For Small Business
    Renmatix 
    The Plantrose® Process: Supercritical Water as the Economic Enabler of Biobased Industry (summary and picture)
  • For Academic
    Professor Eugene Y.-X. Chen of Colorado State University
    Greener Condensation Reactions for Renewable Chemicals, Liquid Fuels, and Biodegradable Polymers (summary and picture)
  • For Specific Environmental Benefit: Climate Change
    Algenol
    The Algenol Biofuel Process: Sustainable Production of Ethanol and Green Crude (summary and picture)

2014 Award Winners

  • For Greener Synthetic Pathways
    Solazyme, Inc. (now Corbion)
    Tailored Oils Produced from Microalgal Fermentation (summary and podcast)
  • For Greener Reaction Conditions
    QD Vision, Inc. (technology acquired by Samsung)
    Greener Quantum Dot Synthesis for Energy Efficient Display and Lighting Products (summary and podcast)
  • For Designing Greener Chemicals
    The Solberg Company (Acquired by Perimeter Solutions)
    RE-HEALINGTM Foam Concentrates–Effective Halogen-Free Firefighting (summary)
  • For Small Business
    Amyris
    Farnesane: a Breakthrough Renewable Hydrocarbon for Use as Diesel and Jet Fuel (summary and podcast)
  • For Academic
    Professor Shannon S. Stahl of the University of Wisconsin-Madison
    Aerobic Oxidation Methods for Pharmaceutical Synthesis (summary and podcast)

2013 Award Winners

  • For Greener Synthetic Pathways
    Life Technologies Corporation (technology acquired by Thermo Fisher Scientific)
    Safe, Sustainable Chemistries for the Manufacturing of PCR Reagents (summary)
  • For Greener Reaction Conditions
    The Dow Chemical Company 
    EVOQUETM Pre-Composite Polymer Technology (summary)
  • For Designing Greener Chemicals
    Cargill, Inc. 
    Vegetable Oil Dielectric Insulating Fluid for High-Voltage Transformers (summary)
  • For Small Business
    Faraday Technology, Inc. 
    Functional Chrome Coatings Electrodeposited from a Trivalent Chromium Plating Electrolyte (summary)
  • For Academic
    Professor Richard P. Wool of the University of Delaware 
    Sustainable Polymers and Composites: Optimal Design (summary)

2012 Award Winners

  • For Greener Synthetic Pathways
    Codexis, Inc.
    Professor Yi Tang of the University of California, Los Angeles
    An Efficient Biocatalytic Process to Manufacture Simvastatin (summary and podcast)
  • For Greener Reaction Conditions
    Cytec Industries Inc.(acquired by Solvay)
    MAX HT® Bayer Sodalite Scale Inhibitor (summary and podcast)
  • For Designing Greener Chemicals
    Buckman International, Inc.
    Enzymes Reduce the Energy and Wood Fiber Required to Manufacture High-Quality Paper and Paperboard (summary and podcast)
  • For Small Business
    Elevance Renewable Sciences, Inc.
    Using Metathesis Catalysis to Produce High-Performing, Green Specialty Chemicals at Advantageous Costs (summary and podcast)
  • For Academic
    Professor Robert M. Waymouth of Stanford University
    Dr. James L. Hedrick of the IBM Almaden Research Center
    Organic Catalysis: A Broadly Useful Strategy for Green Polymer Chemistry (summary and podcast)
  • For Academic
    Professor Geoffrey W. Coates of Cornell University
    Synthesizing Biodegradable Polymers from Carbon Dioxide and Carbon Monoxide (summary and podcast)

2011 Award Winners

  • For Greener Synthetic Pathways
    Genomatica
    Production of Basic Chemicals from Renewable Feedstocks at Lower Cost (summary and podcast)
  • For Greener Reaction Conditions
    Kraton Performance Polymers, Inc.
    NEXARTM Polymer Membrane Technology (summary and podcast)
  • For Designing Greener Chemicals
    The Sherwin-Williams Company
    Water-based Acrylic Alkyd Technology (summary and podcast)
  • For Small Business
    BioAmber, Inc.
    Integrated Production and Downstream Applications of Biobased Succinic Acid (summary and podcast)
  • For Academic
    Professor Bruce H. Lipshutz of the University of California, Santa Barbara
    Towards Ending Our Dependence on Organic Solvents (summary and podcast)

2010 Award Winners

  • For Greener Synthetic Pathways
    The Dow Chemical Company 
    BASF Corporation 
    Innovative, Environmentally Benign Production of Propylene Oxide via Hydrogen Peroxide (summary and podcast)
  • For Greener Reaction Conditions
    Merck & Co., Inc. 
    Codexis, Inc. 
    Greener Manufacturing of Sitagliptin Enabled by an Evolved Transaminase (summary and podcast)
  • For Designing Greener Chemicals
    Clarke 
    NatularTM Larvicide: Adapting Spinosad for Next-Generation Mosquito Control (summary and podcast)
  • For Small Business
    LS9, Inc. (Acquired by Renewable Energy Group) 
    Microbial Production of Renewable PetroleumTM Fuels and Chemicals (summary and podcast)
  • For Academic
    James C. Liao, Ph.D., of the University of California, Los Angeles 
    Easel Biotechnologies, LLC 
    Recycling Carbon Dioxide to Biosynthesize Higher Alcohols (summary and podcast)

2009 Award Winners

  • For Greener Synthetic Pathways
    Eastman Chemical Company 
    A Solvent-Free Biocatalytic Process for Cosmetic and Personal Care Ingredients (summary and podcast)
  • For Greener Reaction Conditions
    CEM Corporation 
    Innovative Analyzer Tags Proteins for Fast, Accurate Results without Hazardous Chemicals or High Temperatures (summary and podcast)
  • For Designing Greener Chemicals
    The Procter & Gamble Company 
    Cook Composites and Polymers Company (Chempol® technology acquired by Arkema Coating Resins) 
    Chempol® MPS Resins and Sefose® Sucrose Esters Enable High-Performance Low-VOC Alkyd Paints and Coatings (summary and podcast)
  • For Small Business
    Virent Energy Systems, Inc.  
    BioForming® Process: Catalytic Conversion of Plant Sugars into Liquid Hydrocarbon Fuels (summary and podcast)
  • For Academic
    Professor Krzysztof Matyjaszewski of Carnegie Mellon University 
    Atom Transfer Radical Polymerization: Low-impact Polymerization Using a Copper Catalyst and Environmentally Friendly Reducing Agents (summary and podcast)

2008 Award Winners

  • For Greener Synthetic Pathways
    Battelle 
    Development and Commercialization of Biobased Toners (summary)
  • For Greener Reaction Conditions
    Nalco Company 
    3D TRASAR® Technology (summary)
  • For Designing Greener Chemicals
    Dow Agrosciences LLC (now CortevaTM Agriscience) 
    Spinetoram: Enhancing a Natural Product for Insect Control (summary)
  • For Small Business
    SiGNa Chemistry, Inc. 
    New Stabilized Alkali Metals for Safer, Sustainable Syntheses (summary)
  • For Academic
    Professors Robert E. Maleczka, Jr. and Milton R. Smith, III of Michigan State University 
    Green Chemistry for Preparing Boronic Esters (summary)

2007 Award Winners

  • For Greener Synthetic Pathways
    Professor Kaichang Li of Oregon State University 
    Columbia Forest Products 
    Hercules Incorporated (now Ashland Inc. )
    Development and Commercial Application of Environmentally Friendly Adhesives for Wood Composites (summary)
  • For Greener Reaction Conditions
    Headwaters Technology Innovation 
    Direct Synthesis of Hydrogen Peroxide by Selective Nanocatalyst Technology (summary)
  • For Designing Greener Chemicals
    Cargill, Incorporated 
    BiOHTM Polyols (summary)
  • For Small Business
    NovaSterilis 
    Environmentally Benign Medical Sterilization Using Supercritical Carbon Dioxide (summary)
  • For Academic
    Professor Michael J. Krische of the University of Texas at Austin 
    Hydrogen-Mediated Carbon–Carbon Bond Formation (summary)

2006 Award Winners

  • For Greener Synthetic Pathways
    Merck & Co., Inc. 
    Novel Green Synthesis for β-Amino Acids Produces the Active Ingredient in JanuviaTM (summary)
  • For Greener Reaction Conditions
    Codexis, Inc. 
    Directed Evolution of Three Biocatalysts to Produce the Key Chiral Building Block for Atorvastatin, the Active Ingredient in Lipitor® (summary)
  • For Designing Greener Chemicals
    S.C. Johnson & Son, Inc. 
    GreenlistTM Process to Reformulate Consumer Products (summary)
  • For Small Business
    Arkon Consultants 
    NuPro Technologies, Inc. (now Eastman Kodak)
    Environmentally Safe Solvents and Reclamation in the Flexographic Printing Industry (summary)
  • For Academic
    Professor Galen J. Suppes of University of Missouri-Columbia 
    Biobased Propylene Glycol and Monomers from Natural Glycerin (summary)

2005 Award Winners

  • For Greener Synthetic Pathways
    Archer Daniels Midland Company 
    Novozymes 
    NovaLipidTM: Low Trans Fats and Oils Produced by Enzymatic Interesterification of Vegetable Oils Using Lipozyme® (summary)
  • For Greener Synthetic Pathways
    Merck & Co., Inc. 
    A Redesigned, Efficient Synthesis of Aprepitant, the Active Ingredient in Emend®: A New Therapy for Chemotherapy-Induced Emesis (summary)
  • For Greener Reaction Conditions
    BASF Corporation 
    A UV-Curable, One-Component, Low-VOC Refinish Primer: Driving Eco-Efficiency Improvements (summary)
  • For Designing Greener Chemicals
    Archer Daniels Midland Company 
    Archer RCTM: A Nonvolatile, Reactive Coalescent for the Reduction of VOCs in Latex Paints (summary)
  • For Small Business
    Metabolix, Inc. (now Yield10 Bioscience)
    Producing Nature's Plastics Using Biotechnology (summary)
  • For Academic
    Professor Robin D. Rogers of The University of Alabama 
    A Platform Strategy Using Ionic Liquids to Dissolve and Process Cellulose for Advanced New Materials (summary)

2004 Award Winners

  • For Greener Synthetic Pathways
    Bristol-Myers Squibb Company 
    Development of a Green Synthesis for Taxol® Manufacture via Plant Cell Fermentation and Extraction (summary)
  • For Greener Reaction Conditions
    Buckman Laboratories International, Inc. 
    Optimyze®: A New Enzyme Technology to Improve Paper Recycling (summary)
  • For Designing Greener Chemicals
    Engelhard Corporation (now BASF Corporation) 
    Engelhard RightfitTM Organic Pigments: Environmental Impact, Performance, and Value (summary)
  • For Small Business
    Jeneil Biosurfactant Company
    Rhamnolipid Biosurfactant: A Natural, Low-Toxicity Alternative to Synthetic Surfactants (summary)
  • For Academic
    Professor Charles A. Eckert and Professor Charles L. Liotta of Georgia Institute of Technology 
    Benign Tunable Solvents Coupling Reaction and Separation Processes (summary)

2003 Award Winners

  • For Greener Synthetic Pathways
    Süd-Chemie Inc. (now Clariant) 
    A Wastewater-Free Process for Synthesis of Solid Oxide Catalysts (summary)
  • For Greener Reaction Conditions
    DuPont 
    Microbial Production of 1,3-Propanediol (summary)
  • For Designing Greener Chemicals
    Shaw Industries, Inc. 
    EcoWorxTM Carpet Tile: A Cradle-to-Cradle Product (summary)
  • For Small Business
    AgraQuest, Inc. (now Bayer CropScience) 
    Serenade®: An Effective, Environmentally Friendly Biofungicide (summary)
  • For Academic
    Professor Richard A. Gross of Rensselaer Polytechnic Institute
    New Options for Mild and Selective Polymerizations Using Lipases (summary)

2002 Award Winners

  • For Greener Synthetic Pathways
    Pfizer, Inc. 
    Green Chemistry in the Redesign of the Sertraline Process (summary)
  • For Greener Reaction Conditions
    Cargill Dow LLC (now NatureWorks LLC) 
    NatureWorksTM PLA Process (summary)
  • For Designing Greener Chemicals
    Chemical Specialties, Inc. (now Viance) 
    ACQ Preserve®: The Environmentally Advanced Wood Preservative (summary)
  • For Small Business
    SC Fluids, Inc.
    SCORR – Supercritical CO2 Resist Remover (summary)
  • For Academic
    Professor Eric J. Beckman of the University of Pittsburgh
    Design of Non-Fluorous, Highly CO2-Soluble Materials (summary)

2001 Award Winners

  • For Greener Synthetic Pathways
    Bayer Corporation
    Bayer AG (technology acquired by LANXESS) 
    BaypureTM CX (Sodium Iminodisuccinate): An Environmentally Friendly and Readily Biodegradable Chelating Agent (summary)
  • For Greener Reaction Conditions
    Novozymes North America, Inc. 
    BioPreparationTM of Cotton Textiles: A Cost-Effective, Environmentally Compatible Preparation Process (summary)
  • For Designing Greener Chemicals
    PPG Industries 
    Yttrium as a Lead Substitute in Cationic Electrodeposition Coatings (summary)
  • For Small Business
    EDEN Bioscience Corporation (technology acquired by Plant Health Care, Inc.) 
    Messenger®: A Green Chemistry Revolution in Plant Production and Food Safety (summary)
  • For Academic
    Professor Chao-Jun Li of McGill University 
    Quasi-Nature Catalysis: Developing Transition Metal Catalysis in Air and Water (summary)

2000 Award Winners

  • For Greener Synthetic Pathways
    Roche Colorado Corporation (now CordenPharma Colorado) 
    An Efficient Process for the Production of Cytovene, a Potent Antiviral Agent (summary)
  • For Greener Reaction Conditions
    Bayer Corporation (now Covestro) 
    Bayer AG
    Two-Component Waterborne Polyurethane Coatings (summary)
  • For Designing Greener Chemicals
    Dow AgroSciences LLC   
    SentriconTM Termite Colony Elimination System, A New Paradigm for Termite Control (summary)
  • For Small Business
    RevTech, Inc.
    EnvirogluvTM: A Technology for Decorating Glass and Ceramicware with Radiation-Curable, Environmentally Compliant Inks (summary)
  • For Academic
    Professor Chi-Huey Wong of The Scripps Research Institute   
    Enzymes in Large-Scale Organic Synthesis (summary)

1999 Award Winners

  • For Greener Synthetic Pathways
    Lilly Research Laboratories 
    Practical Application of a Biocatalyst in Pharmaceutical Manufacturing (summary)
  • For Greener Reaction Conditions
    Nalco Company 
    The Development and Commercialization of ULTIMER®: The First of a New Family of Water-Soluble Polymer Dispersions (summary)
  • For Designing Greener Chemicals
    Dow AgroSciences LLC 
    Spinosad: A New Natural Product for Insect Control (summary)
  • For Small Business
    BioFine, Inc. (now DPS BioMetics, Inc.)
    Conversion of Low-Cost Biomass Wastes to Levulinic Acid and Derivatives (summary)
  • For Academic Award
    Professor Terry Collins of Carnegie Mellon University
    TAMLTM Oxidant Activators: General Activation of Hydrogen Peroxide for Green Oxidation Technologies (summary)

1998 Award Winners

  • For Greener Synthetic Pathways
    Flexsys America L.P. (now Eastman Chemical Company) 
    Elimination of Chlorine in the Synthesis of 4-Aminodiphenylamine: A New Process That Utilizes Nucleophilic Aromatic Substitution for Hydrogen (summary)
  • For Greener Reaction Conditions
    Argonne National Laboratory 
    Novel Membrane-Based Process for Producing Lactate Esters – Nontoxic Replacements for Halogenated and Toxic Solvents (summary)
  • For Designing Greener Chemicals
    Rohm & Haas Company (now a subsidiary of The Dow Chemical Company) 
    Invention and Commercialization of a New Chemical Family of Insecticides Exemplified by CONFIRMTM Selective Caterpillar Control Agent and the Related Selective Insect Control Agents MACH 2TM and INTREPIDTM (summary)
  • For Small Business
    PYROCOOL Technologies, Inc.
    Technology for the Third Millennium: The Development and Commercial Introduction of an Environmentally Responsible Fire Extinguishment and Cooling Agent (summary)
  • For Academic
    Professor Barry M. Trost of Stanford University 
    The Development of the Concept of Atom Economy (summary)
  • For Academic
    Dr. Karen M. Draths and Professor John W. Frost of Michigan State University
    Use of Microbes as Environmentally Benign Synthetic Catalysts (summary)

1997 Award Winners

  • For Greener Synthetic Pathways
    BHC Company (now BASF Corporation) 
    BHC Company Ibuprofen Process (summary)
  • For Greener Reaction Conditions
    Imation (technology acquired by Eastman Kodak Company) 
    DryViewTM Imaging Systems (summary)
  • For Designing Greener Chemicals
    Albright & Wilson Americas (now Rhodia, a member of the Solvay Group) 
    THPS Biocides: A New Class of Antimicrobial Chemistry (summary)
  • For Small Business
    Legacy Systems, Inc. (now Modutek Corporation)
    ColdstripTM, A Revolutionary Organic Removal and Wet Cleaning Technology (summary)
  • For Academic
    Professor Joseph M. DeSimone of Stanford University 
    Design and Application of Surfactants for Carbon Dioxide (summary)

1996 Award Winners

  • For Greener Synthetic Pathways
    Monsanto Company 
    Catalytic Dehydrogenation of Diethanolamine (summary)
  • For Greener Reaction Conditions
    The Dow Chemical Company 
    100 Percent Carbon Dioxide as a Blowing Agent for the Polystyrene Foam Sheet Packaging Market (summary)
  • For Designing Greener Chemicals
    Rohm & Haas (now a subsidiary of The Dow Chemical Company) 
    Designing an Environmentally Safe Marine Antifoulant (summary)
  • For Small Business
    Donlar Corporation (NanoChem Solutions, Inc., part of Flexible Solutions) 
    Production and Use of Thermal Polyaspartic Acid (summary)
  • For Academic
    Professor Mark Holtzapple of Texas A&M University
    Conversion of Waste Biomass to Animal Feed, Chemicals, and Fuels (summary)
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Last updated on April 4, 2023
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