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Pesticide Registration

Pesticide Registration Notices by Category

The Office of Pesticide Programs Pesticide Registration (PR) Notices to inform pesticide registrants and other interested persons about important policies, procedures and regulatory decisions.They do not create new legally binding requirements.

This listing by category is intended to help you find the notices that are most relevant to your issue. PR notices can be listed in more than one category.

Note that this listing may not be comprehensive. That is, there could be notices that include content in a category, but that content was not identified when this categorization was developed. There also may be other categories that were not identified when we developed this list. If you find items in either category or have other questions about this list, please contact us

View PR Notices listed by the year they were issued.

On this page:

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Draft notices

  • Draft PR Notice 2016-X - Guidance for Pesticide Registrants on Pesticide Resistance Management Labeling Search EPA Archive
  • Draft PR Notice 2016-XX - Guidance for Herbicide Resistance Management Labeling, Education, Training, and Stewardship Search EPA Archive
  • Draft PR Notice 2012-X - Guidance for Antimicrobial Pesticide Products with Mold-Related Label Claims. Docket ID EPA-HQ-OPP-2010-0539.
  • Draft PR Notice 2010-X - Proposed Guidance on False or Misleading Pesticide Product Brand Names. Docket ID EPA-HQ-OPP-2010-0282.
  • Draft PR Notice 2007-A - Guidance for Antimicrobial Pesticide Products With Anthrax-Related Claims. Docket ID EPA-HQ-OPP-2006-1004.
  • Draft PR Notice 2006-B (9/29/06) - Guidance on Small-Scale Field Testing and Low-level Intermittent Presence in Food of Plant-Incorporated Protectants (PIPs)  Docket ID EPA-HQ-OPP-2006-0291.
  • Draft PR Notice 2006-A (09/22/2006) - Draft Pesticide Registration Notice Use of Antimicrobial Pesticide Products in Heating, Ventilation, Air Conditioning and Refrigeration Systems (HVAC&R)
  • Draft PR Notice 2002-X (03/14/02) - False or Misleading Pesticide Product Brand Names
  • Draft PR Notice 2001-X (8/9/01) - Spray and Dust Drift Label Statements for Pesticide Products
  • Draft PR Notice 2000-X (3/29/00)- Indoor Residential Insecticide Product

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Pesticide Registration

All Pesticide Registration

  • PR  Notice 2018-1 - Pesticides: Guidance for Registrants on the Determination of Minor Use
  • PR Notice 2017-1Guidance for Pesticide Registrants on Pesticide Resistance Management Labeling
  • PR Notice 2017-2  - Guidance for Herbicide Resistance Management Labeling, Education, Training, and Stewardship
  • Draft PR Notice 2016-X - Guidance for Pesticide Registrants on Pesticide Resistance Management Labeling Search EPA Archive
  • Draft PR Notice 2016-XX - Guidance for Herbicide Resistance Management Labeling, Education, Training, and StewardshipSearch EPA Archive
  • PR Notice 2011-3 - Standard Format for Data Submitted under FIFRA
  • PR Notice 2008-1 - Environmental Hazard General Labeling Statements on Outdoor Residential Use Products
  • PR Notice 2007-4 - Labeling Revisions Required by the Federal Rule "Pesticide Management and Disposal: Standards for Pesticides Containers and Containment
  • PR Notice 2000-5- Guidance for Mandatory and Advisory Labeling Statements
  • PR Notice 98-1 - Self Certification of Product Chemistry Data with Attachments
  • PR Notice 98-10 - Notifications, Non-notifications, and Minor Formulation Amendments
  • PR Notice 95-2 - Notifications, Non-Notifications & Minor Formulation AmendmentsSearch EPA Archive
  • PR Notice 90-1 - Inert Ingredients in Pesticide Products; Revised Policy Statement
  • PR Notice 87-1 - Label Improvement Program for Pesticides Applied through Irrigation Systems (Chemigation)
  • PR Notice 87-6 - Inert Ingredients in Pesticide Products Policy Statement

Antimicrobial Pesticide Product Registration

  • Draft PR Notice 2012-X - Guidance for Antimicrobial Pesticide Products with Mold-Related Label Claims. Docket ID EPA-HQ-OPP-2010-0539.
  • PR Notice 2008-2 - Antimicrobial Pesticide Products With Anthrax-Related Claims
  • Draft PR Notice 2007-A - Guidance for Antimicrobial Pesticide Products With Anthrax-Related Claims. Docket ID EPA-HQ-OPP-2006-1004.
  • Draft PR Notice 2006-A - (09/22/2006) Draft Pesticide Registration Notice Use of Antimicrobial Pesticide Products in Heating, Ventilation, Air Conditioning and Refrigeration Systems (HVAC&R)
  • PR Notice 2002-X - Draft False or Misleading Pesticide Product Names
  • PR Notice 2001-4 - Elimination of Phenol Resistance Testing for Antimicrobial Disinfectant and Sanitizer Pesticides
  • PR Notice 2000-10 (12/20/00)- Changes to "Effective Date and Procedures" for PR Notice 2000-1, "Applicability of the Treated Articles Exemption to Antimicrobial Pesticides"
  • PR Notice 2000-5 - Guidance for Mandatory or Advisory Labeling Statements
  • PR Notice 2000-1 - Applicability of the Treated Articles Exemption to Antimicrobial Pesticides.
    • A Fact Sheet on this PR Notice is also available.
  • PR Notice 98-10 - Notifications, Non-Notifications and Minor Formulation Amendments
  • PR Notice 98-8 - Waiver of Fees Associated with Tolerance Objections
  • PR Notice 98-2 - Liquid Chemical Sterilant Products
  • PR Notice 97-9 - Electronic Submission of Child-Resistant Packaging Test Data for all Pesticides and Child-Resistant Testing of Prefilled, Nonrefillable Insecticide Bait Stations not Designed or Intended to be Opened or Activated in a Manner that Exposes the Contents to Human Contact
  • PR Notice 97-7 - Existing Stocks for Labeling Changes in PR Notices
  • PR Notice 97-6 - Use of Term "Inert" in the Label Ingredients Statement
  • PR Notice 97-5 - Use of Common Names for Active Ingredients on Pesticide Labeling
  • PR Notice 97-1 - Agency Actions under the Requirements of the Food Quality Protection Act
  • PR Notice 96-2 - Changes to Child-Resistant Packaging (CRP) Testing Requirements
  • PR Notice 95-5 - New Chemical, New Use and EUP Priorities for Conventional Pesticides
  • PR Notice 95-2 - Notifications, Non-Notifications and Minor Formulation AmendmentsSearch EPA Archive
  • PR Notice 95-1 - Effluent Discharge Labeling Statements
  • PR Notice 94-4 - Interim Measures for the Registration of Antimicrobial Products/Liquid Chemical Germicides with Medical Device Use Claims Under the Memorandum of Understanding Between EPA and FDA
  • PR Notice 94-2 - Recycling Empty Aerosol Pesticide Containers
  • PR Notice 93-10 - Effluent Discharge Labeling Statements
  • PR Notice 93-6 - False or Misleading Statements related to Efficacy; Revision of PR Notice 91-7
  • PR Notice 93-4 - Ban on Aerosol Products Containing CFCs and HCFCs under the Clean Air Act
  • PR Notice 92-2 - Permissible Label Claims Regarding Ozone Depleting Substances
  • PR Notice 91-7 - False and Misleading Statements Search EPA Archive
  • PR Notice 91-2 - Accuracy of Stated Percentages for Ingredients Statements
  • PR Notice 90-1 - Inert Ingredients in Pesticide Products; R
  • PR Notice 88-2 - Clustering of Quaternary Ammonium Compounds 
  • PR Notice 86-5 -Standard Format for Data Submitted Under the FIFRA and Certain Provisions of the FFDCA
  • PR Notice 83-3 - Label Improvement Program - Storage and Disposal Statements
  • PR Notice 81-4 - Label Improvement Program - Label Revisions to Accommodate New AOAC Methods of Chemical Analysis
  • PR Notice 81-3 - Label Improvement Program: Change in Test Methods for and Categorzation of Eye Irritation Search EPA Archive
  • PR Notice 75-5 - Unacceptable Use of the Word "Chlorine" in the Name and Labeling of Pesticides
  • PR Notice 70-16 - Requirements for Additional Labeling on Products Containing Sodium Hypochlorite
  • PR Notice 67-5 - Economic Poisons Containing Sodium Hypochlorite
  • PRN 66 - Federal Registration of Economic Poisons

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FIFRA Data Requirements and Submission of Data

  • PR Notice 2011-3 - Standard Format for Data Submitted Under the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) and Certain Provisions of the Federal Food, Drug, and Cosmetic Act (FFDCA)
  • PR Notice 2001-2 - Acute Toxicity Data Requirements For Granular Pesticide Products, Including Those With Granular Fertilizers in the Product.
  • PR Notice 98-5 - New forms for the Certification with Respect to Citation of Data
  • PR Notice 98-1 - Self-Certification of Product Chemistry Data with Attachments
  • PR Notice 97-9 - Electronic Submission of Child-Resistant Packaging Test Data for all Pesticides and Child-Resistant Testing of Prefilled, Nonrefillable Insecticide Bait Stations not Designed or Intended to be Opened or Activated in a Manner that Exposes the Contents to Human Contact
  • PR Notice 96-2 - Changes to Child-Resistant Packaging (CRP) Testing Requirements
  • PR Notice 94-1 - Withdrawal of PR Notice 91-8
  • PR Notice 93-2  - Waiver of Crop Field Trial Data for Aerial Applications

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FIFRA Exemptions and Supplementary Guidelines

  • PR  Notice 2018-1 - Pesticides: Guidance for Registrants on the Determination of Minor Use
  • PR Notice 2000-6 - Minimum Risk Pesticides Exempted under FIFRA Section 25(b) Clarification of Issues.
    • UPDATE: Appendix B in this notice was amended as of August 2004. LIST 4A Minimal Risk Inerts
  • PR Notice 99-1 - Import of Unregistered Pesticides Intended for Export
  • PR Notice 98-8 - Waiver of Fees Associated with Tolerance Objections
  • PR Notice 98-2 - Liquid Chemical Sterilant Products
  • PR Notice 97-3 - Guidelines for Expedited Review of Conventional Pesticides under the Reduced-Risk Initiative and for Biological Pesticides
  • PR Notice 94-4 - Interim Measures for the Registration of Antimicrobial Products/Liquid Chemical Germicides with Medical Device Use Claims Under the Memorandum of Understanding Between EPA and FDA
  • PR Notice 93-4 - Ban on Aerosol Products Containing CFCs and HCFCs under the Clean Air Act

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Incident Reporting

  • PR Notice 2000-8 – Reportability of Attorneys’ Opinions and Conclusions Under 40 CFR Part 159 and FIFRA Section 6(a)(2)
  • PR Notice 98-4 - Additional Guidance on Final FIFRA Section 6(a)(2) Regulations for Pesticide Product Registrants w/Attachment
  • PR Notice 98-3 - Guidance on Final FIFRA 6(a)(2) Regulations for Pesticide Product Registrants
  • PR Notice 92-1 - Requirement to submit and identify adverse effects information

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FQPA Guidelines

  • PR Notice 97-1 - Agency Actions under the Requirements of the Food Quality Protection Act

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Labeling

Pesticide Product Labels

  • PR Notice 2017-1Guidance for Pesticide Registrants on Pesticide Resistance Management Labeling
  • PR Notice 2017-2 - Guidance for Herbicide Resistance Management Labeling, Education, Training, and Stewardship
  • Draft PR Notice 2016-X - Guidance for Pesticide Registrants on Pesticide Resistance Management Labeling Search EPA Archive
  • Draft PR Notice 2016-XX - Guidance for Herbicide Resistance Management Labeling, Education, Training, and Stewardship Search EPA Archive
  • Draft PR Notice 2012-X – Guidance for Antimicrobial Pesticide Products with Mold-Related Label Claims. Docket ID EPA-HQ-OPP-2010-0539.
  • Draft PR Notice 2010-X - Proposed Guidance on False or Misleading Pesticide Product Brand Names. Docket ID EPA-HQ-OPP-2010-0282.
  • Draft PR Notice 2002-X (03/14/02) - False or Misleading Pesticide Product Brand Names
  • PR Notice 2008-1 - Environmental Hazard General Labeling Statements on Outdoor Residential Use Products
    • [was withdrawn]
  • PR Notice 2007-4 (revised 5/08) - Labeling Revisions Required by the Final Rule “Pesticide Management and Disposal; Standards for Pesticide Containers and Containment
  • PR Notice 2005-1  - Labeling Statements on Products Used for Adult Mosquito Control
  • PR Notice 2003-1 - Clarification Of PR Notice 2003-1
  • PR Notice 2003-1 - Labeling of Pesticide Products under the National Organic Program
    • Clarification of PR Notice 2003-1
  • Draft PR Notice 2001-X (8/9/01) - Spray and Dust Drift Label Statements for Pesticide Products
  • PR Notice 2001-5 - Guidance for Pesticide Registrants on Pesticide Resistance Management Labeling Search EPA Archive
  • Draft PR Notice 2000-X (3/29/00)- Indoor Residential Insecticide Product Label Statements.
  • PR Notice 2000-5 - Guidance for Mandatory and Advisory Labeling Statements.
  • PR Notice 98-10 - Notifications, Non-notifications, and Minor Formulation Amendments
  • PR Notice 97-8 - Time Extension of PR Notice 96-7 - Termiticide Labeling
  • PR Notice 97-7 - Existing Stocks for Labeling Changes in PR Notices
  • PR Notice 97-4 - Consumer Access Numbers on Pesticide Labels
  • PR Notice 96-7 - Termiticide Labeling
  • PR Notice 96-6 - Pet Pesticide Product Label Statements
  • PR Notice 95-2 - Notifications, Non-Notifications & Minor Formulation AmendmentsSearch EPA Archive
  • PR Notice 94-6 - Pesticide Products Registered for Use on Humans to Control Lice (Pediculicides)
  • PR Notice 93-6 - False or Misleading Statements Related to Efficacy; Revision of PR Notice 91-7
  • PR Notice 93-1 - Statement of Restricted Use Classification
  • PR Notice 91-1 - Procedures for Voluntarily Requesting Deletion of Approved Uses from Registered Labels

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Labeling for Environmental Issues

  • PR Notice 2008-1 - Environmental Hazard General Labeling Statements on Outdoor Residential Use Products
    • [was withdrawn]
  • PR Notice 2007-4 (revised 5/08) - Labeling Revisions Required by the Final Rule “Pesticide Management and Disposal; Standards for Pesticide Containers and Containment
  • PR Notice 96-4 - Label Statements Involving Product Efficacy and Potential for Harm to Property
  • PR Notice 93-8 - Labeling Statement Prohibiting Application to Water; Amendment to PR Notice 93-3
  • PR Notice 93-3 - Labeling Statement Prohibiting Application to Water
  • PR Notice 93-5 - Labeling Requirements of the Clean Air Act
  • PR Notice 93-4 - Ban on Aerosol Products Containing CFCs and HCFCs under the Clean Air Act

Labeling Safety Requirements

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Label Ingredients Statements

  • PR Notice 97-6 - Use of Term "Inert" in the Label Ingredients Statement
  • PR Notice 97-5 - Use of Common Names for Active Ingredients on Pesticide Labeling
  • PR Notice 96-8 - Toxicologically Significant Levels of Pesticide Active Ingredients
  • PR Notice 92-2 - Permissible label claims regarding ozone depleting substances
  • PR Notice 91-2 - Accuracy of Stated Percentages for Ingredients Statement
  • PR Notice 90-1 - Inert Ingredients in Pesticide Products; Revised Policy Statement
  • PR Notice 87-6 - Inert Ingredients in Pesticide Products Policy Statement
  • PR Notice 72-6 - Changes in standard for expressing potency of products containing BACILLUS TRURINGIENSIS BERLINERSearch EPA Archive
  • PR Notice 70-16 - Requirements for Additional Labeling on Products Containing Sodium Hypochlorite

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Label Improvement Program

  • PR Notice 94-7 - Label Improvement Program for the Revision of Use Directions for Commensal Rodenticides and Statement of the Agency's Policies on the Use of Rodenticide Bait Stations
  • PR Notice 87-1 - Label Improvement Program for Pesticides Applied through Irrigation Systems (Chemigation)
  • PR Notice 85-6 - Clarification of Label Improvement Program for Fumigants. Revision of PR Notice 84-5
  • PR Notice 84-5 - Label Improvement Program for Fumigants
  • PR Notice 84-1 - Clarification of Label Improvement Program
  • PR Notice 83-3 - Label Improvement Program - Storage and Disposal Statements
  • PR Notice 81-4 - Label Improvement Program - Label Revisions to accommodate new OAOC Methods of Chemical analysis
  • PR Notice 80-2 - Label Improvement Program: Deletion of salt water emesis statements

Web-Distributed Labeling

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Product Packaging

  • PR Notice 2007-4 (revised 5/08) - Labeling Revisions Required by the Final Rule “Pesticide Management and Disposal; Standards for Pesticide Containers and Containment
  • PR Notice 97-9 - Electronic Submission of Child-Resistant Packaging Test Data for all Pesticides and Child-Resistant Testing of Prefilled, Nonrefillable Insecticide Bait Stations not Designed or Intended to be Opened or Activated in a Manner that Exposes the Contents to Human Contact
  • PR Notice 96-2 - Changes to Child-Resistant Packaging (CRP) Testing Requirements
  • PR Notice 94-8 - Water Soluble Packaging (WSP)

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Pesticides and Health

  • PR Notice 2011-1 - Residential Exposure Joint Venture
  • PR Notice 2007-2 - Guidance on Small-Scale Field Testing and Low-level Presence in Food of Plant-Incorporated Protectants (PIPs)
  • Draft PR Notice 2006-B (9/29/06) - Guidance on Small-Scale Field Testing and Low-level Intermittent Presence in Food of Plant-Incorporated Protectants (PIPs) Docket ID EPA-HQ-OPP-2006-0291.
  • PR Notice 2002-2 - Guidance for Submitting Requests for Threshold of Regulation (TOR) Decisions to the Office of Pesticide Programs
  • PR Notice 2002-1 - Lists of Pests of Significant Public Health Importance
  • PR Notice 96-8  - Toxicologically Significant Levels of Pesticide Active Ingredients
  • PR Notice 96-5 - Interim Use of the Proposed Guidelines for Carcinogen Risk AssessmentSearch EPA Archive
  • PR Notice 96-3 - Pesticide Products Used to Disinfect Aircraft
  • PR Notice 96-1 - Tolerance Enforcement Methods - Independent Laboratory Validation by Petitioner
  • PR Notice 95-4 - Regulatory Status of Methyl Bromide and Priority Review of Methyl Bromide Alternatives
  • PR Notice 94-5 - Requests for Re-considerations of Carcinogenicity Peer Review Decisions Based on Changes in Pathology Diagnoses
  • PR Notice 93-9 - Voluntary Reduced-Risk Pesticides Initiative
  • PR Notice 73-4 - Residual Insecticides in Food handling Establishments

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Experimental Use Permits

  • PR Notice 2003-2 - Expedited Review of Experimental Use Permits for New Uses of Conventional Methyl Bromide Alternatives, Organophosphate (OP) Alternatives, and/or Reduced-Risk PesticidesSearch EPA Archive
  • Draft PR Notice 2001-X (12/19/01) - Guidelines for Expedited Review of Experimental Use Permits for Conventional Pesticides.
  • PR Notice 97-2 - New Chemical, New Use, EUP, Non-Fast Track Amendments and Inert Ingredient Registration Priorities for Conventional Pesticides Search EPA Archive
  • PR Notice 95-6 - New Chemical, New Use and EUP Priorities for Conventional Pesticides

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Worker Risk and the Worker Protection Standard (WPS)

  • PR Notice 2000-9 - Worker Risk Mitigation for Organophosphate Pesticides Search EPA Archive
    • Response to Public Comments on the Draft Pesticide Registration Notice on Worker Risk Mitigation for Organophosphate Pesticides
    • PR Notice 95-5 - Labeling Revisions Required by the Worker Protection Attachments (PDF) (13 pp, 495 K)
    • PR Notice 95-3 - Reduction of Worker Protection Standard (WPS)
    • PR Notice 93-11 - Supplemental Guidance for PR Notice 93-7 - Labeling Revisions Required by the Worker Protection Standard (WPS)
    • PR Notice 93-7 - Labeling Revisions Required by the Worker Protection Standard (WPS)

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Disposal Instruction

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Registration Task Forces

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OPP General Notices/Procedures

  • PR Notice 2006-1 - New Instructions for Transmitting Information to the Office of Pesticide Programs, including New Addresses
  • PR Notice 2004-1 - Change of address for personal and courier deliveries to the Office of Pesticide Programs - Obsolete
  • PR Notice 2003-3 - Procedural Guidance for EPA's Office of Pesticide Programs Procedures Concerning the Development, Modification, and Implementation of Policy Guidance Documents
  • PR Notice 2002-2 - Guidance for Submitting Requests for Threshold of Regulation (TOR) Decisions to the Office of Pesticide Programs
  • PR Notice 88-6 - Change in Registration Procedures; Agency Approval not Required for Certain Amendments

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