Ongoing and Completed Chemical Risk Evaluations under TSCA
The existing chemicals listed on this page have either undergone or are currently undergoing risk evaluation as part of EPA’s existing chemical process under the Toxic Substances Control Act (TSCA) to determine whether they present an unreasonable risk to public health or the environment.
Learn more about:
- The risk evaluation process for existing chemicals under TSCA
- The prioritization process, and how chemicals are identified as a high priority for risk evaluation
- Manufacturer-requested risk evaluations
- Risk management for existing chemicals
Chemical Name | CASRN | Chemical Group | Date Initiated | Docket Number(s) | Status* | Agency Contact |
---|---|---|---|---|---|---|
1-Bromopropane (1-BP) | 106-94-5 | Solvents | December 2016 | EPA-HQ-OPPT-2019-0235; EPA-HQ-OPPT-2016-074 | Final risk evaluation (August 2020), Proposed risk management rule (July 2024) | Olivia Bailey Email: 1BP_TSCA@epa.gov Phone: (202) 566-0894 |
1,1-Dichloroethane | 75-34-3 | Solvents | December 2019 | EPA-HQ-OPPT-2018-0426, EPA-HQ-OPPT-2024-0114 | Final risk evaluation (June 2025) | Clara Hull Email: 1.1.Dichloroethane.TSCA@epa.gov Phone: (202) 564-3954 |
1,1,2-Trichloroethane | 79-00-5 | Solvents | December 2019 | EPA-HQ-OPPT-2018-0421 | Final scope (August 2020) | Matthew Lloyd Email: Lloyd.matthew@epa.gov Phone: (202) 566-2389 |
1,2-Dichloroethane | 107-06-2 | Solvents | December 2019 | EPA-HQ-OPPT-2018-0427, EPA-HQ-OPPT-2024-0114 | Draft human health hazard (July 2024) | Simon Regenold Email: 1.2.Dichloroethane.TSCA@epa.gov Phone: (202) 566-1537 |
1,2-Dichloropropane | 78-87-5 | Solvents | December 2019 | EPA-HQ-OPPT-2018-0428 | Final scope (August 2020) | Clara Hull Email: Hull.clara@epa.gov Phone: (202) 564-3954 |
1,3-Butadiene | 106-99-0 | N/A | December 2019 | EPA-HQ-OPPT-2018-0451, EPA-HQ-OPPT-2024-0425 | Final scope (August 2020); Draft risk evaluation (December 2024) | Brooke Porter Email: Porter.brooke@epa.gov Phone: (202) 564-6388 |
1,3,4,6,7,8-Hexahydro-4,6,6,7,8,8-hexamethylcyclopenta [g]-2-benzopyran (HHCB) | 1222-05-5 | Fragrance additives | December 2019 | EPA-HQ-OPPT-2018-0430 | Final scope (August 2020) | Jeffrey Putt Email: Putt.jeffrey@epa.gov Phone: (202) 564-3703 |
1,4-dioxane | 123-91-1 | Solvents | December 2016 | EPA-HQ-OPPT-2019-0238; EPA-HQ-OPPT-2016-0723; EPA-HQ-OPPT-2022-0905 | Final risk evaluation (December 2020); Final supplement (November 2024) | Cindy Wheeler Email: Wheeler.cindy@epa.gov Phone: (202) 566-0484 |
4,4'-(1-Methylethylidene)bis[2, 6-dibromophenol] (TBBPA) | 79-94-7 | Flame retardants | December 2019 | EPA-HQ-OPPT-2018-0462 | Final scope (August 2020) | Chloe O'Haire |
Asbestos | 1332-21-4 | N/A | December 2016 | EPA-HQ-OPPT-2016-0736; EPA-HQ-OPPT-2019-0501; EPA-HQ-OPPT-2021-0254 | Part 1: Final risk evaluation (December 2020), Final risk management rule (March 2024) Part 2: Draft risk evaluation (April 2024), Final risk evaluation (November 2024) | Robert Courtnage Email: courtnage.robert@epa.gov Phone: (202) 566-1081 |
Butyl benzyl phthalate - 1,2-Benzene- dicarboxylic acid, 1- butyl 2(phenylmethyl) ester (BBP) | 85-68-7 | Phthalates | December 2019 | EPA-HQ-OPPT-2018-0501 | Draft risk evaluation (August 2025) | Brianne Raccor Email: Raccor.brianne@epa.gov Phone: 202-564-0303 |
Carbon Tetrachloride (CTC) | 56-23-5 | Solvents | December 2016 | Final risk evaluation (November 2020), Final risk management rule (December 2024) | Emilia Echeveste Briseño Email: CarbonTetrachlorideTSCA@epa.gov Phone: (202) 566-0543 | |
C.I. Pigment Violet 29 (PV29) | 81-33-4 | Pigments | December 2016 | EPA-HQ-OPPT-2018-0604; EPA-HQ-OPPT-2016-0725 | Final risk evaluation (January 2021), Proposed risk management rule (December 2024) | Carolyn Mottley Email: Mottley.carolyn@epa.gov Phone: (202) 566-1955 |
Cyclic Aliphatic Bromide Cluster (HBCD) | 25637-99-4; 3194-55-6; 3194-57-8 | Flame retardants | December 2016 | EPA-HQ-OPPT-2019-0237; EPA-HQ-OPPT-2016-0735 | Final risk evaluation (September 2020) | Brianne Raccor Email: Raccor.brianne@epa.gov Phone: 202-564-0303 |
Di-ethylhexyl phthalate - (1,2-Benzene- dicarboxylic acid, 1,2- bis(2-ethylhexyl) ester) (DEHP) | 117-81-7 | Phthalates | December 2019 | EPA-HQ-OPPT-2018-0433 | Draft risk evaluation (June 2025) | Dyllan Taylor Email: Taylor.dyllan@epa.gov Phone: (202) 564-2913 |
Di-isobutyl phthalate - (1,2-Benzene- dicarboxylic acid, 1,2- bis-(2methylpropyl) ester) (DIBP) | 84-69-5 | Phthalates | December 2019 | EPA-HQ-OPPT-2018-0434 | Draft risk evaluation (July 2025) | Robert Landolfi Email: Landolfi.robert@epa.gov Phone: (202) 343-9161 |
Di-isodecyl phthalate – (1,2-benzenedicarboxylic acid 1,2-diisodecyl ester) (DIDP) | 26761-40-0, 68515-49-1 | Phthalates | December 2019 | EPA-HQ-OPPT-2018-0435; EPA-HQ-OPPT-2024-0073 | Final risk evaluation (December 2024) | Brianne Raccor Email: Raccor.brianne@epa.gov Phone: 202-564-0303 |
Di-isononyl phthalate – (1,2-benzenedicarboxylic acid, 1,2-diisononyl ester) (DINP) | 28553-12-0; 68515-48-0 | Phthalates | December 2019 | EPA-HQ-OPPT-2018-0436; EPA-HQ-OPPT-2024-0073 | Final risk evaluation (January 2025) | Todd Coleman Email: Coleman.todd@epa.gov Phone: (202) 564-1208 |
Dibutyl phthalate (1,2-Benzene- dicarboxylic acid, 1,2- dibutyl ester) (DBP) | 84-74-2 | Phthalates | December 2019 | EPA-HQ-OPPT-2018-0503 | Draft risk evaluation (June 2025) | Carolyn Mottley Email: Mottley.carolyn@epa.gov Phone: (202) 566-1955 |
Dicyclohexyl phthalate (DCHP) | 84-61-7 | Phthalates | December 2019 | EPA-HQ-OPPT-2018-0504 | Draft risk evaluation (January 2025) | Claire Brisse Email: Brisse.claire@epa.gov Phone: (202) 564-9004 |
Ethylene dibromide | 106-93-4 | N/A | December 2019 | EPA-HQ-OPPT-2018-0488 | Final scope (August 2020) | Bethany Masten Email: EthyleneDibromide.TSCA@epa.gov Phone: (202) 564-8803 |
Formaldehyde | 50-00-0 | N/A | December 2019 | EPA-HQ-OPPT-2023-0613; EPA-HQ-OPPT-2018-0438 | Final risk evaluation (December 2024) | Jeffrey Putt Email: Putt.jeffrey@epa.gov Phone: (202) 564-3703 |
Methylene Chloride | 75-09-2 | Solvents | December 2016 | EPA-HQ-OPPT-2019-0437; EPA-HQ-OPPT-2016-0742 | Final risk evaluation (June 2020), Final risk management rule (April 2024) | Email: MethyleneChlorideTSCA@epa.gov Ingrid Feustel Phone: (202) 564-3199 Daniel Whitby Phone: 202-564-0598 |
N-Methylpyrrolidone (NMP) | 872-50-4 | Solvents | December 2016 | EPA-HQ-OPPT-2019-0236; EPA-HQ-OPPT-2016-0743 | Final risk evaluation (December 2020), Proposed risk management rule (June 2024) | Clara Hull Email: NMP.TSCA@epa.gov Phone: (202) 564-3954 |
o-Dichlorobenzene | 95-50-1 | N/A | December 2019 | EPA-HQ-OPPT-2018-0444 | Final scope (August 2020) | Peter Deck Email: oDCB.TSCA@epa.gov Phone: (202) 566-0488 |
Octamethylcyclotetra- siloxane (D4) | 556-67-2 | N/A | October 2020 | EPA-HQ-OPPT-2018-0443 | Final scope (March 2022) | Scott Drewes Email: Drewes.scott@epa.gov Phone: (202) 564-8833 |
p-Dichlorobenzene | 106-46-7 | N/A | December 2019 | EPA-HQ-OPPT-2018-0446 | Final scope (August 2020) | Ingrid Feustel Email: pDCB.TSCA@epa.gov Phone: (202) 564-3199 |
Perchloroethylene (PCE) | 127-18-4 | Solvents | December 2016 | EPA-HQ-OPPT-2019-0502; EPA-HQ-OPPT-2016-0732 | Final risk evaluation (December 2020), Final risk management rule (December 2024) | Kelly Summers Email: PCE.TSCA@epa.gov Phone: (202) 564-2201 |
Phosphoric acid, triphenyl ester (TPP) | 115-86-6 | Flame retardants | December 2019 | EPA-HQ-OPPT-2018-0458 | Final scope (August 2020) | Chloe O'Haire Email: Ohaire.chloe@epa.gov Phone: (202) 564-6785 |
Phthalic anhydride | 85-44-9 | N/A | December 2019 | EPA-HQ-OPPT-2018-0459 | Final scope (August 2020) | Wyn Zenni Email: Zenni.Wyn@epa.gov Phone: (202)564-6294 |
trans-1,2- Dichloroethylene | 156-60-5 | Solvents | December 2019 | EPA-HQ-OPPT-2018-0465 | Final scope (August 2020) | Daniel Whitby Email: Whitby.daniel@epa.gov Phone: (202) 564-0598 |
Trichlorethylene (TCE) | 79-01-6 | Solvents | December 2016 | EPA-HQ-OPPT-2016-0737; EPA-HQ-OPPT-2019-0500; EPA-HQ-OPPT-2020-0642 | Final risk evaluation (November 2020), Final risk management rule (December 2024) | Gabriela Rossner Email: TCE.TSCA@epa.gov Phone: (202) 565-2426 |
Tris(2-chloroethyl) phosphate (TCEP) | 115-96-8 | Flame retardants | December 2019 | EPA-HQ-OPPT-2018-0476; EPA-HQ-OPPT-2023-0265 | Final Risk Evaluation (September 2024) | Chloe O'Haire Email: Ohaire.chloe@epa.gov Phone: (202) 564-6785 |
Acetaldehyde | 75-07-0 | December 2023 | EPA-HQ-OPPT-2018-0497 | Final designation (December 2024) | Kathleen Ferry Email: Ferry.Kathleen@epa.gov Phone: (202) 564-2214 | |
Acrylonitrile | 107-13-1 | December 2023 | EPA-HQ-OPPT-2018-0449 | Final designation (December 2024) | Wyn Zenni Email: Zenni.wyn@epa.gov Phone: (202) 564-6294 | |
Benzenamine | 62-53-3 | December 2023 | EPA-HQ-OPPT-2018-0474 | Final designation (December 2024) | Maxim Pohl Email: Pohl.maxim@epa.gov Phone: (202) 566-2827 | |
Vinyl Chloride | 75-01-4 | December 2023 | EPA-HQ-OPPT-2018-0448 | Draft scope (January 2025) | Bethany Masten Email: VinylChloride.TSCA@epa.gov Phone: (202) 564-8803 | |
4,4’ Methylene bis(2-chloraniline) (MBOCA) | 101-14-4 | December 2023 | EPA-HQ-OPPT-2018-0464 | Final designation (December 2024) | Emilia Echeveste-Briseno Email: Echevestebriseno.emilia@epa.gov Phone: (202) 566-0543 |
* Status: “Initiated”: Chemicals that have been designated as a high priority or for which risk evaluation has begun. “Draft Scope”: EPA has published a draft scope document for public comment. “Final Scope”: EPA has published a final scope document (or problem formulation for the first 10). “Draft risk evaluation”: EPA has published a draft risk evaluation. “Final risk evaluation”: EPA has completed a final risk evaluation. "Proposed risk management rule": EPA has published a draft risk management rule. "Final risk management rule": EPA has published a final risk management rule.