Skip to main content
U.S. flag

An official website of the United States government

Here’s how you know

Dot gov

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

HTTPS

Secure .gov websites use HTTPS
A lock (LockA locked padlock) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

    • Environmental Topics
    • Air
    • Bed Bugs
    • Cancer
    • Chemicals, Toxics, and Pesticide
    • Emergency Response
    • Environmental Information by Location
    • Health
    • Land, Waste, and Cleanup
    • Lead
    • Mold
    • Radon
    • Research
    • Science Topics
    • Water Topics
    • A-Z Topic Index
    • Laws & Regulations
    • By Business Sector
    • By Topic
    • Compliance
    • Enforcement
    • Laws and Executive Orders
    • Regulations
    • Report a Violation
    • Environmental Violations
    • Fraud, Waste or Abuse
    • About EPA
    • Our Mission and What We Do
    • Headquarters Offices
    • Regional Offices
    • Labs and Research Centers
    • Planning, Budget, and Results
    • Organization Chart
    • EPA History

Breadcrumb

  1. Home
  2. TRI National Analysis

Chemical Profiles

In this section, we take a closer look at some of the Toxics Release Inventory (TRI) chemicals of interest to the public, the Environmental Protection Agency (EPA), lawmakers, and industry. These profiles include chemicals that are classified by the TRI Program as chemicals of special concern, such as chemicals that are persistent, bioaccumulative, and toxic (PBTs), and carcinogens (chemicals that cause cancer).

PBT chemicals are not only toxic, but they also break down slowly in the environment and tend to build up (bioaccumulate) in organisms throughout the food web. These organisms are food sources for other organisms, including humans, which are sensitive to the toxic effects of PBT chemicals. Reporting thresholds classified by the TRI Program as chemicals of special concern are either 10 pounds or 100 pounds, which is much lower than the reporting threshold for most TRI chemicals. For dioxin and dioxin-like compounds, the reporting threshold is even lower, at 0.1 gram. The chemicals of special concern covered in this section are lead and lead compounds, mercury and mercury compounds, dioxin and dioxin-like compounds, and per- and polyfluoroalkyl substances (PFAS).

You can generate a fact sheet for any TRI chemical using TRI Explorer.


Previous Next

This page was published in March 2024 and uses the 2022 TRI National Analysis dataset made public in TRI Explorer in October 2023.

TRI National Analysis

  • TRI Program Home
  • Introduction
    • TRI Data Considerations
  • Pollution Prevention
    • Source Reduction Activities
    • Source Reduction Activities by Chemical & Industry
    • Green Chemistry & Engineering Activities
    • Reported Barriers to Source Reduction
    • Source Reduction Activities by Parent Company
  • Waste Management
    • Trends in Waste Management
    • Waste Management by Chemical & Industry
    • Non-Production-Related Waste Managed
    • Waste Managed by Parent Company
  • Releases of Chemicals
    • Trends in Releases
    • Releases by Chemical & Industry
    • Potential Risks from TRI Chemicals
      • Hazard & Risk-Screening Trend
    • Air Releases
      • Air Releases by Chemical & Industry
    • Water Releases
      • Water Releases by Chemical & Industry
    • Land Disposal
      • Land Disposal by Chemical & Industry
  • Chemical Profiles
    • Lead
    • Mercury
    • Dioxins
    • Ethylene Oxide
    • Carcinogens
    • PFAS
  • Comparing Industry Sectors
    • Manufacturing Sectors
      • Manufacturing Waste Management Trend
    • Chemical Manufacturing
      • Chemical Manufacturing Waste Management Trend
      • Greenhouse Gas Reporting in the Chemical Manufacturing Sector
    • Primary Metals Manufacturing
      • Primary Metals Waste Management Trend
    • Metal Mining
      • Metal Mining Waste Management Trend
    • Electric Utilities
      • Electric Utilities Waste Management Trend
      • Greenhouse Gas Reporting in the Electric Utilities Sector
    • Federal Facilities
      • Federal Facilities by Industry
      • Waste Management by Federal Facilities
  • Where You Live
    • EPA Regions
    • States & Metropolitan Areas
    • Watersheds
    • Tribal Communities
  • TRI Connections
    • TRI Around the World
    • Mapping Cross-Border Transfers
  • Past National Analyses
Contact Us About the TRI National Analysis
Contact Us to ask a question, provide feedback, or report a problem.
Last updated on March 3, 2025
  • Assistance
  • Spanish
  • Arabic
  • Chinese (simplified)
  • Chinese (traditional)
  • French
  • Haitian Creole
  • Korean
  • Portuguese
  • Russian
  • Tagalog
  • Vietnamese
United States Environmental Protection Agency

Discover.

  • Accessibility Statement
  • Budget & Performance
  • Contracting
  • EPA www Web Snapshot
  • Grants
  • No FEAR Act Data
  • Plain Writing
  • Privacy
  • Privacy and Security Notice

Connect.

  • Data
  • Inspector General
  • Jobs
  • Newsroom
  • Regulations.gov
  • Subscribe
  • USA.gov
  • White House

Ask.

  • Contact EPA
  • EPA Disclaimers
  • Hotlines
  • FOIA Requests
  • Frequent Questions
  • Site Feedback

Follow.